Is puppy crying after lepto vaccine normal? How long does it last?

My suspicion is that this is injection-site pain and not a "true" vaccine reaction, however I do know that dogs (especially small ones) can be pretty painful in the limb they were vaccinated in for up to 36 hours afterwards. I wouldn't call it "normal" but we definitely see it - both of my own small dogs were painful after their last lepto vaccine. Because they can be pretty miserable, I would recommend calling your vet and asking if they might dispense a bit of pain relief - perhaps only 2 - 3 days worth - to make sure Ted is comfortable over the weekend. And if you see other more concerning signs - swelling about the head or face, difficulty breathing, vomiting, collapse - take him right into an emergency facility.

Getting vaccines can be stressful and painful to the dog, and Scrappy may be feeling a little off from all the stress of the day. I would continue to monitor him, and I would be worried if he starts having protected vomiting or diarrhea, develops a swollen face and muzzle, and starts having trouble breathing. Those can be signs of a rare but serious vaccine reaction, and in that case, I'd take him into a vet right away. Try putting a cold compress on where he received his lepto vaccine to see if that helps him. You can apply for 5-10 minutes a couple of times a day. Typically a dog is back to normal within 24-48 hours after a vaccine. Best of luck, I hope this helps.

While not considered a "core" vaccine, the leptospirosis vaccine is highly recommended for dogs who may be at risk for contracting leptospirosis, as it is a disease that can lead to agonizing deaths in both animals and humans. See the links below for more information: https://www.avma.org/public/PetCare/Pages/Leptospirosis.aspx https://ebusiness.avma.org/files/productdownloads/LR_COM_ClientBroch_Leptospirosis_022616.pdf

Thanks for using Petco Pet Education Center, formerly Petcoach! Possible side effects after vaccines include pain at the injection site, lethargy, inappetence and general discomfort. This should subside within 1-2 days. If it does not improve or it worsens, have Lily evaluated by a veterinarian for further assessment and treatment. Otherwise, Lily will likely start feeling better shortly. Good luck and best wishes!

Well that depends on the severity of the adverse reaction. If she is having a mild vaccine reaction (1 bout of vomiting, loose stool), then an anti-histamine (i.e. Benadryl) can be given in most cases and will calm the reaction down. However if she is having a more severe adverse reaction (i.e. continuous vomiting, anaphylaxis, severe lethargy, anorexia), then she will need an antihistamine shot (for immediate reversal), +/- steroid shot from your vet , +/- fluid therapy and close monitoring to ensure that the reaction subsides and that she remains stable.

I'm sorry to hear that Lettie is not feeling like her usual self! It should be noted that even normal puppy vaccines can lead to some side effects such as lethargy (decreased activity, tiredness), swelling or tenderness around the injection site and even mild nausea (possibly the drooling). That being said, rarely dogs can undergo an allergic reaction to vaccines which often show up as vomiting, collapse, and swelling of the face or other limbs. If these have been observed she should be seen by a veterinarian immediately. In regards to the safety of administering the Heartguard and Nexgard along with the vaccines, it is standard protocol to begin these preventative medications at this time and are safe to give to a puppy of Lettie's age. The most important thing going forward is to continue to monitor Lettie for any worsening or changing of her clinical signs. For example, if she starts to vomit becomes even more tired or lethargic, continues to want to eat or do anything after more than a day, or even have swelling around her face then she needs to be seen by a veterinarian immediately.

You can see some pain where the vaccines were given. Do not give Penelope any human pain relievers, many are toxic to dogs and can be fatal if given. You can try putting a cold compress on the area where she got her vaccines to see if that helps. She should be back to normal within 24 hours, but if she isn't, have her seen by a vet. Best of luck.