Why is my dog shaking and heart rate high after Lepto vaccine?

My suspicion is that this is injection-site pain and not a "true" vaccine reaction, however I do know that dogs (especially small ones) can be pretty painful in the limb they were vaccinated in for up to 36 hours afterwards. I wouldn't call it "normal" but we definitely see it - both of my own small dogs were painful after their last lepto vaccine. Because they can be pretty miserable, I would recommend calling your vet and asking if they might dispense a bit of pain relief - perhaps only 2 - 3 days worth - to make sure Ted is comfortable over the weekend. And if you see other more concerning signs - swelling about the head or face, difficulty breathing, vomiting, collapse - take him right into an emergency facility.

Well that depends on the severity of the adverse reaction. If she is having a mild vaccine reaction (1 bout of vomiting, loose stool), then an anti-histamine (i.e. Benadryl) can be given in most cases and will calm the reaction down. However if she is having a more severe adverse reaction (i.e. continuous vomiting, anaphylaxis, severe lethargy, anorexia), then she will need an antihistamine shot (for immediate reversal), +/- steroid shot from your vet , +/- fluid therapy and close monitoring to ensure that the reaction subsides and that she remains stable.

I would be concerned in that vomiting isn't a typical reaction after receiving vaccines, but it's good that Toby seems completely find otherwise. To be safe, I would give the vet who gave him the vaccines a call. Vomiting after vaccines can be a sign of an allergic reaction, and your vet may want to see him. If you can't reach his vet, watch him very closely. Should the vomiting continue, or he develops other signs such severe coughing, difficulty breathing, itchy skin, hives, or swelling of the face, rush him into an ER vet right away. I hope this helps!

Good on you for getting your puppies their lepto vaccines! When puppies get their vaccines, it can be painful for them at the injection site for around 24-48 hours, and that is normal. I would avoid carrying them if it makes them cry, and you can try putting a cold compress on site if they will let you for five minutes at a time a couple of times of day to see if that helps. Please do not give them any human pain medications, as many are toxic to puppies and can be fatal if given. This pain should go away in a day or two. If it doesn't, give the vet a call, as they may want to see the puppies. As for side effects, typically you would see them develop within 24 hours of the vaccines. Keep an eye on them for now, but serious side effects are rare and they should be fine. I hope this helps!

While not considered a "core" vaccine, the leptospirosis vaccine is highly recommended for dogs who may be at risk for contracting leptospirosis, as it is a disease that can lead to agonizing deaths in both animals and humans. See the links below for more information: https://www.avma.org/public/PetCare/Pages/Leptospirosis.aspx https://ebusiness.avma.org/files/productdownloads/LR_COM_ClientBroch_Leptospirosis_022616.pdf

It could be that Starla may have a mild fever, which can be a common side effect after receiving vaccines. She may have some pain or discomfort as well at the site of the injections. These side effects should clear up in a day or two, but I would monitor her breathing for now. Should she experience difficulty breathing, this is not normal, and you will have to take her into the vet immediately.

You can see a mild fever after vaccines, and that could be the cause of Jack's shaking. Benadryl will not help with that if he has a fever. Keep an eye on him, and if the shaking continues for more than 24 hours or he develops other signs such as persistent vomiting and diarrhea, hives, swelling of the muzzle, and/or difficulty breathing, take him into a vet immediately. Best of luck.