Petco Text Logo
Petco Pet Logo
  • Two Easy Ways to Start Earning Rewards!

    rewards header
    Become a member today!
    Members-only pricing and offers, personalized care notifications, Vital Care points back on every purchase and more!
    Petco Pay LogoBecome a credit card member today!

    Earn 2X Pals Rewards points at Petco
    when you use Petco Pay!

    APPLY NOW
    Learn More About Petco Pay Benefits

Is my dog's scratching a Nexgard side effect? What should I do?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Female | 4 years and 10 months old | 92 lbs

I gave my dog fle & tick Nexgard about 5 hrs ago for the 1st time and ever since shes been scratching and biting herself non stop. Shes miserable. Is this a side effect? What can i do to help

2 Answers

Most Helpful Answer

Debi Matlack

Answered By Debi Matlack

Veterinary Technician

Published on December 15th, 2020

It has been known to cause local skin irritation, but the itching could mean that it is working if she had fleas on her. I would see if there is a number on the package to call for advice. If the itching continues into tomorrow or if she's actually injuring herself with the scratching or starts having other symptoms such as lethargy, loss of appetite, vomiting, etc., get her seen by your vet as soon as possible.
Vote Icon1Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Answered By Dr. Leigh, DVM

    Veterinarian

    Published on January 26th, 2017

    Lethargy and lack of appetite can occassionally be seen in dogs after NexGard but it could be unrelated to the medication. She should be examined by your vet to determine the cause. Your vet can give her some fluids and an anti-inflammatory to make her feel better. Also, discuss with your vet whether you should continue using NexGard next month. Hope she feels better soon!

    Vote Icon

    1Pet Parents found this answer helpful

Smart Picks for Smart Questions

Have A Vet Question?

Book an appointment with the pros – our expert vets are here to help.

Share

Styled arrow button