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My dog is peeing often with blood. Could her cancer be spreading?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female

My dog has just peed twice with probably less than an hour in between those two urinations, something we've never seen her do before. Additionally, in the second puddle of urine, we noticed she had blood mixed in with it. We don't know what exactly was the cause, but, considering she has cancer in one of her nipples and in her left leg, we're thinking that her cancer has spread.

4 Answers

Most Helpful Answer

Answered By Sarah Derksen, DVM

Veterinarian

Published on February 11th, 2018

Poor girl. So sorry to hear she has cancer. Frequent urination, blood in the urine, and small amounts can be a sign of a urinary tract infection, bladder or kidney stones, bladder inflammation, or bladder cancers. Without some testing and an exam, we can't say for sure which of those it is. We will hope for something simple. She will need an exam, a urine test, and some xrays of that bladder. Give your veterinarian a call in the morning for an appointment.

1Pet Parents found this answer helpful

Related Answers from Veterinarians

Answered By Dr. Elizabeth
Veterinarian
Published on November 17th, 2017
Queeny is very cute! Blood in the urine generally indicates an infection, urinary crystals or bladder stones. All of these are generally uncomfortable as well. I would recommend to take Queeny into the veterinarian as soon as you can to have her urine checked. The doctor may recommend further diagnostics based the on the results. She will receive pain medications which will make her feel better. I hope this helps!
1Pet Parents found this answer helpful
Answered By Dr. Macartney, BVet Med, MRCVS
Veterinarian
Published on October 25th, 2017
I am very sorry to hear that Henney is unwell. If you are noticing accidents in the house and now blood in her urine it is very likely that Henney has a urinary tract issue. This could be cystitis or inflammation/infection of the bladder or an issue higher up in her kidneys. My advice is to take her to a vet as soon as you can to have the issue diagnosed with a urine analysis and have a treatment plan developed for Henney.

Best of luck to you both and please post any further questions you may have. We are here to help you!
1Pet Parents found this answer helpful
Answered By Jennifer Summerfield, DVM CPDT-KA
Veterinarian, Certified Dog Trainer
Published on July 18th, 2017
Poor DazyMay! Stress should not cause bloody urine in dogs, so I would be concerned that she probably has a medical issue causing this, such as a urinary tract infection or bladder stones. I would recommend taking her to the vet when you can to have this checked - he/she can do a urinalysis as well as x-rays or ultrasound of her bladder if needed to help determine the problem and get her started on appropriate treatment.
1Pet Parents found this answer helpful

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My dog has bladder cancer and is peeing blood. Is she suffering?

The blood could be coming from the tumor itself, or sometimes dogs with tumors are more likely to develop urinary tract infections. If she is also straining to urinate it may be that her quality of life is beginning to be affected. Before you make any decisions you should recheck with your vet. They could check her urine for bacteria and can also discuss what signs to look for that might indicate it is time to consider euthanasia.

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Why is my older dog peeing blood and urinating often without pain?

Poor Snic! Frequent urination with blood at the end of the urine stream could be caused by a few different things - even if she doesn't act painful, this is definitely not normal. The most common causes of these symptoms in an older female dog like Snic would include a bacterial UTI, bladder stones, or even a bladder tumor of some kind. I would recommend taking Snic to the vet for an exam as soon as you are able to - he/she can do a urinalysis and may also recommend x-rays or ultrasound of her bladder to help diagnose the problem and get her started on appropriate treatment.

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Why is my dog peeing blood if her urine tests are normal?

Blood in the urine is never normal, even if it only occurs intermittently. Likewise, it’s unusual for Tilly to experience so much inconsistency in her urination habits. Some young female dogs can have recessed or hooded vulvas, which can make them more prone to developing urinary tract infections. However, since Tilly’s urine has twice not shown evidence of infection, it sounds as though it’s time to look in a different direction. I would start by asking your vet if they can take x-rays of her abdomen to check for evidence of bladder stones. The crystals associated with bladder stones often show up on a urinalysis (I’m assuming that’s what was done with her urine samples), but not always. If the X-rays are clear, your next step may be an ultrasound of her bladder with a veterinary radiologist to check for any other abnormalities. Bladder tumors can also cause similar signs, although that would be highly unlikely given how young Tilly is. I hope this helps and that you can find some answers soon!

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My young dog has a bladder mass and bloody urine. Is it cancer?

It could be that Chika has urinary stones causing the mass in her bladder and the red color of her urine. Another possibility could be a canine polypoid eosinophilic cystitis, also known as benign inflammatory fibrous polyp. In a year and half old dog, bladder cancer would be rare, so I wouldn't have that at the top of my differential list. I know it's scary, but I try not to get too worried just yet until you have the mass diagnosed. I hope this helps!

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Why is my dog peeing blood and having seizures? Is it serious?

I'm so sorry to hear that. Bloody urine can have a number of different causes. It can be due to a problem in the urinary tract-- such as a severe urinary tract infection, bladder stones, or a bladder tumor. Those things may also cause her to urinate frequently in small amounts and/or strain to urinate (but not necessarily). It could also be a problem higher up in her urinary tract--in her ureters (tube from kidney to bladder) or in her kidneys-- again an infection, stone or tumor. The other potential cause of seeing blood in the urine is if she isn't able to form a blood clot properly. If her blood platelets or clotting factors are low or are not working correctly, bleeding can occur within the bladder (or anywhere in the body--bruising under the skin, bleeding around the gums, blood in the stool, bloody nose, blood in the eyes). We can also sometimes see the urine look bloody when its actually a different thing causing the pigment (color). For instance, if she's destroying her red blood cells and the pigment (color) from the red blood cells which is the hemoglobin is ending up in her urine. Also myoglobin (which occurs with massive muscle damage) can result in dark reddish brown urine. Some types of toxic ingestions can also result in reddish brown urine. The seizure on Sunday makes me more concerned that something very serious is going on with her. If she's unable to clot her blood properly she could have a bleed in her brain. Or the seizures may be completely unrelated to the urine. I wish I could offer you a suggestion to treat her at home, but it sounds like you need to have her seen by a veterinarian as soon as you can.

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Why is my old dog peeing blood and having accidents indoors?

He could have a urinary tract infection so he should be examined by a vet. Your vet can run a urinalysis to look for infection and other potential causes. He could also have urinary stones, prostate problem, tumor, etc. If he has an infection then he will need an antibiotic to treat.

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My dog has bladder cancer. Is her frequent urination painful? How can I tell?

Hello, sorry to hear about Tiki. It depends on why she is having these frequent small urinations. Masses in the bladder can indeed cause an increase in urgency and dogs may want to urinate more frequently without having much pee to expel. Unfortunately, depending on where the tumor is, if it is blocking the urine outflow tract, then the frequency of her attempts may be associated with being unable to urinate completely and thus needing to go more often. This process can indeed be be painful. If painful, Tiki may vocalize (whine, cry, yelp) when urinating. If she ever is unable to urinate, then she will need to be seen on emergency basis for this. Monitor for any vocalization while urinating, bloody urine, or straining to urinate and not producing any urine for over a 6 hour period. You may also see vomiting and a decreased appetite with complications associated with this mass. If you note any of these then have Tiki evaluated promptly. Dogs with bladder tumors typically do show improvement of their symptoms when on the piroxicam, so if she is not getting any better, your veterinarian may need to reassess her medication protocol and options. Hope this helps and best of luck.

Updated on September 23rd, 2025

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