Why does my dog need to take Palladia for cancer for the rest of her life?

A response would be expected within 4-6weeks of starting paladia. Given the severity of symptoms you describe, I would recommend review by an oncologist to assess what else, if anything can be added or adjusted to improve her comfort and quality of life. Frequent histamine episodes are definitely cause for concern and consideration of euthanasia is a very valid option at this stage.

I am sorry to hear of Tsunami's diagnosis and although paladia could theoretically be a good treatment choice it does not sound like it would be a good fit for her lifestyle. The serious restrictions required for safe use could be very stressful both for her and your family and yes, discussion of safer alternatives with her primary treating vet or oncologist would be a very responsible course to take. Even though treatment may not be as successful, a full assessment of benefits and risks is warranted for the safety of everyone in your household

I am sorry your dog is suffering from lymphosarcoma. He will need to take the prednisone for the rest of his life as that slows down the cancer. There is no need to wean him off. You will need to discuss this with your veterinarian.

Thanks for using Petco Pet Education Center, formerly Petcoach! Lymphoma is in fact a cancer. This is typically treated with chemotherapy. There are many chemotherapy options that can be considered such as a multi agent protocol called CHOP. There are other chemotherapeutic medications that can be considered depending on what your veterinarian has available. In general, chemotherapy is well-tolerated in dogs when done appropriately. If not able to proceed with chemotherapy, there are other options like prednisone therapy alone which in itself can help dogs with lymphoma though for a very short amount of time. The prognosis with chemotherapy varies and depends on the type of lymphoma he has (B-cell vs. T-cell) and the treatment chosen. The prognosis varies between 6 to 12 months with chemotherapy and about 2 months on just prednisone. Please feel free to request a consultation with me if you have more specific questions. Good luck!

I believe I provided you with the answer to this question before regarding the tapering. Now that I know that he is being treated for MCT, I would recommend speaking to your vet regarding the treatment. Prednisone is not generally considering the gold standard treatment for this condition. If he has not offered you a referral to an oncologist, I would request one if you are looking to pursue any other therapies. One of the best therapies available right now for Mast Cell Tumors is a drug called Palladia. I would love to consult with you concerning Hachi's condition including this drug and a possible tapering schedule if you were not clear on the answer I provided you earlier. Just let me know or one of the other experts here so we can try and find a way to make Hachi more comfortable.

First off, I'm sorry that Roxy has lymphoma (cancer of the lymph nodes)! Yes, your vet is correct that this treatment protocol can give her more time with you. Each dog responds differently to the treatment, but with chemotherapy, the median survival time is 6-12 months. Given I can't see her in person, I can't say for certain how long she is survive, but I do recommend following your vet's recommendations to increase your time with her. Again, I'm sorry about her diagnosis :-(

I'm sorry to hear that Daisy received this diagnosis. There are certainly risks and benefits to both options with respect to side effects, life span and cost. Side effects of prednisone in the short term can cause excessive drinking and urination. Some animals with underlying heart disease can go into congestive heart failure and other animals can develop diabetes as a result of the high doses of corticosteroids given in these situations. Around 40% of dogs can achieve remission for 4-6 weeks with prednisone alone, but this is certainly based upon an individual's response to medication and if any metastatic (spread) of disease is present. Obviously, this treatment is much less expensive, but a much shorter survival time is expected. Daisy's chemotherapy protocol is based on whether she has B cell or T cell lymphoma and if any metastatic disease is present. As a generalized statement, lymphoma responds to chemotherapy better than most cancers. Oncologists strive to administer chemotherapeutic drugs at doses that will kill cancerous cells while avoiding as many side effects as possible. The side effects possible vary with different chemotherapeutic drugs. In short, there is no right or wrong choice. You need to evaluate both options to determine your comfort level. If you haven't already done so, consider a consultation with a veterinary oncologist for more information. I hope this helps!