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Is Optimune for dry eye causing glaucoma or conflicting with Dorzolamide?

Updated on September 23rd, 2025

Pet's info: Dog | Yorkshire Terrier | Female | spayed | 7.5 lbs

My dog was prescribed Optimune for dry eye (to increase fluid) about 6 months ago. At the time, her eye pressure was 16 in both eyes. Today her eye pressure is 25 (R) and 20 (L) and she has been prescribed Dorzolamide for glaucoma (which is supposed to REDUCE FLUID in the eye). My question: Are the two medications working against each other? And, is it possible that the Optimune caused, or contributed to, the glaucoma issue? Thank you!

1 Answer

Most Helpful Answer

Alysia Van Scoy, DVM

Answered By Alysia Van Scoy, DVM

Veterinarian

Published on October 16th, 2017

No- they are not working against each other and no- the Optimune did not cause it. The Optimmune increases the body's tear production which keeps the clear part of the eye-the cornea- moist. If it gets dry- it suspectible to injuries & gets secondary changes. Glaucoma is caused by increase pressure in the vitreous (the ball part of the eye) which is different than the tears. The tears are external and the vitreous internal. Hope that makes sense. Sounds like you have a great vet who is treating Lanie well! Thanks for reaching out to Petco Pet Education Center, formerly Petcoach .
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