Distemper in my litter. Can I give 5-in-1 vaccines to other pups?
You can give any puppy a vaccine as long as their temperature is normal and they are not actively sick. However, you do run the risk of vaccinating a puppy who already has been exposed, but just hasn't had a full display of symptoms yet. This is an unfortunate situation to be in.
Eye mucous is not a clear sign of distemper, but instead it would entail the full scope of the disease which is lethargy, not eating, fever, upper airway infection symptoms, etc. I would suggest getting a vet involved to do a full exam on these puppies first to determine which are not healthy enough for vaccination, and then try to isolate the sick ones to hopefully help prevent the entire litter from catching it. Hopefully you can save a few of these puppies. Treatment for distemiper is costly and very rarely will result in survival. It is just a terrible disease and I hope the best for your pups as they try to get through this. Best wishes and take care.
Updated on September 23rd, 2025