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Updated on September 23rd, 2025
Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 60 lbs
Our dog has ITP and had 3 blood transfusion while at the emergency vet hospital. The vet told us they don't need to crossmatch if they did them all within 48 hours. Is this true? I cannot find anythjing online stating that.
2 Answers

Answered By Sara Farmer, DVM
Veterinarian
Published on December 3rd, 2017
Answered By Lauren Jones VMD
Veterinarian
The reason that we crossmatch dogs for whole blood or packed red blood cell transfusions is to determine if antibodies are present that could destroy the donor cells, which can cause anaphylactic reactions. I have read that theoretically, there is up to a 4 day window before this antibody development may occur, but it is still recommended to perform blood typing and crossmatching before any blood transfusion. Ideally, this even includes the very first transfusion, but at minimum, should be performed for all subsequent transfusions. That said, if Venus is receiving other blood products, such as fresh frozen plasma (FFP), blood typing and crossmatching is much less of a concern since there are very few red blood cells, and thus fewer antibodies. I hope this helps and that Venus makes a full recovery! She's adorable!
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