My dog got Dex/Benadryl before shots. Will it affect vaccine immunity?

Treating an autoimmune disease should be the priority over vaccinations. The dose of prednisone that you mentioned, should not suppress his immune system or prevent the vaccination from working, however I would discuss this with your vet. In some types of autoimmune disease, I will delay all vaccinations at is can cause flares in the disease process.

A vaccine reaction is usually caused by an abnormal reaction of the immune system to the vaccine, these two medications suppress the immune system and by doing that they usually stop these reactions.

A short course of predisone is unlikely to have any adverse effects in an otherwise healthy dog but may be of more risk if she has other, underlying health conditions? It may however reduce the efficacy of the vaccine and limit the protection this gives her against rabies. It would be worth telephoning the clinic to assess the risks and benefits of her particular case if she has a complicated medial history

The dexamethasone should not make Kai vomit. I recommend to have him examined as the vomiting could be related to the initial allergic reaction. The bland diet should also help settle the tummy but it won’t stop a continuing allergic reaction. I hope this is helps.

Thank you for submitting your question regarding Bella. I try to avoid chronic high doses of steroids in dogs whenever possible as there are side effects internally and externally. However, an injection to control a reaction is not something that concerns me if she is not taking other medications. Steroids can interfere with certain drugs. If her veterinarian deams it necessary after seeing her, then I would go ahead and have it administered. Great question!

Your dog should get an antihistamine before the vaccination. You should ask your vet about giving him a diphenhydramine , or chlorpheniramine injection about an hour before getting the vaccination. This should avoid the reaction or at least reduce the impact. Your veterinarian should have these injectables available.

Antibiotics would not affect the immune system’s ability to respond to a vaccine. If he has a significant infection there might be some concern but if he’s been on the antibiotics for a little while and does not have a fever the vaccines should be effective.