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My dog ate Tylenol. What are the signs of acetaminophen poisoning?

Updated on September 23rd, 2025

Pet's info: Dog | American Pit Bull Terrier | Female | spayed | 65 lbs

My eight year old pitbull ate two 500mg Tylenol last night what should i wach for she also hs a sprained back ankle i guess you woul call it

2 Answers

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on July 26th, 2017

The effects of acetaminophen poisoning in dogs are quite serious, often causing non-repairable liver damage. Dogs will typically experience acetaminophen toxicity at over 75 mg per kg body weight - Lady Girl ingested 1000mg and the toxic dose for her would be around 2,200 mg (if she truly is 65#). She may be OK or she may get sick. There is no way to know. At this point you will just have to monitor her and see.

The most common symptoms that you may notice in pets suffering from acetaminophen toxicity include:

Brownish-gray colored gums
Labored breathing
Swollen face, neck or limbs
Hypothermia (reduced body temperature)
Vomiting
Jaundice (yellowish color to skin, whites of eyes), due to liver damage
Coma

If you notice any of those signs you need to get her to a vet right away.

If she has a problem with her hock (ankle) you need to get her to a vet for an exam. That way you get a proper diagnosis as to what is actually wrong with her leg and then get a medication made for dogs to help her.

DO NOT give any more acetaminophen or any other over the counter medications without talking to your vet first.

I hope this helps. Best wishes to you and Lady Girl. I will keep my fingers crossed that she won't have any adverse effects.
Vote Icon12Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Answered By Linda G, MS, DVM

    Veterinarian

    Published on November 12th, 2019

    Hello. Icy will be OK, as long as she does not get any more acetaminophen, & she does not already receive other medications & does not have any underlying liver or kidney problems. Generally, toxicity is only noted if a pet ingests more than 100 mg/kg, which would be 1400 mg for a dog Icy's size. So a one time 650 mg will not be harmful to her unless she does have some of the issues I already mentioned. If this is the case, please call your regular veterinarian immediately. Thanks for using Petco Pet Education Center, formerly Petcoach.

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    19Pet Parents found this answer helpful

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