My dog ate Aleve. Is 100mg safe for a 40lb dog? What should I do?

I am sorry to hear about your concern for Bandit. Eating one tablet of 220mg of aleve would be a dose of 6.4 mg per kg of body weight in your dog. According to data at the ASPCA, this dose primarily results in GI symptoms such as anorexia, vomiting, diarrhea, and sometimes GI bleeding. Treatment may include gastrointestinal protectants to help coat and soothe the GI tract, fluid therapy to help any dehydration due to diarrhea, so these are things your vet may recommend. If your dog is geriatric or has any concern for prior kidney disease then they can be at increased risk for kidney damage and bloodwork may be recommended to monitor for this.

Hello. Cora consumed the equivalent of 9.7 mg/kg of naproxin. We begin to see GI signs like vomiting & diarrhea, possibly with blood at 7 mg/kg & kidney damage at 13 mg/kg. Since there are other factors that may impact how badly Cora may react to the medication, including any preexisting conditions, dehydration, etc., I think it would be prudent to take Cora to an emergency clinic for decontamination & any possible treatment. I think she should be fine, but better safe than sorry. Thanks for using Petco Pet Education Center, formerly Petcoach.

The only case report of a severe toxic reaction in a dog after a single dose of Alleve involved an elderly dachshund that received 35.7 mg/kg of the drug. your dog received approximately 6.5 mg/kg, fortunately this is not likely to cause any serious toxic reaction, inducing vomiting is not needed in this case but in the future i strongly recommend avoiding this medication altogether as well as any other pain killer from your personal cabinet.

Considering that Naproxen has a very narrow safety margin and a maximum dose of 2mg/kg is described in literature, your dog would have received a seven-fold dose, ie 500mg /35kg = 14 mg/kg, thus making it likely that he may develop some stomach and kidney trouble. I would recommend that you call ASPCA's poison control number. That number is 888-426-4435. There is a $65 charge, but they will be able to best advise you. Please have the label available so you can let them know the amount of medication listed and what any other potentially concerning ingredients were.  I hope thats helpful, thanks for using Petco Pet Education Center, formerly Petcoach

Aleve (naproxen) is definitely concerning and has a small margin of safety in dogs. One of the most common problems it causes is gastrointestinal damage - this would explain the vomiting and diarrhea. However, she can also have kidney and/or liver damage with this drug. Considering she is showing signs of toxicity today, it's best to take her to the vet for an evaluation and treatment. There are good treatment options for these cases that will keep Lilita from getting any worse. It's good that she still seems in good spirits, but it's definitely possible that she can get worse over the next couple of days. For this reason, it's best to take her to a vet as soon as possible. For more information, I recommend you click the link below. http://www.petpoisonhelpline.com/poison/nsaids/ I hope that helps and Lilita gets better soon.

Most cases of toxicosis occur in dogs that are repeatedly given Naproxen. I did find in an article online (the link is below if you want to read the entire article) that "The APCC data suggest that a one-time dose of 7 mg/kg or greater can cause clinical signs of GI irritation and ulceration (vomiting, diarrhea, melena, anorexia), whereas azotemia (elevation of kidney levels) is possible at doses ranging from 13 to 15 mg/kg." Based on your dogs weight of 44 pounds, if he ate one 250 mg tablet then the dose would have been 12.5 mg/kg. The best thing would be to have your vet check kidney values 24-48 hours after the ingestion to make sure all values are normal. Hope this information helps! http://veterinarymedicine.dvm360.com/toxicology-brief-naproxen-toxicosis-dogs?id=&pageID=1&sk=&date=

Roscoe should be taken to the nearest veterinary ER. Vomiting can be induced via injection to get the pill out before it is digested and absorbed. Activated charcoal may be administered afterwards to further reduce absorption. These actions are most successful when done within 2 hours of ingestion. Medication to prevent ulcers may be dispensed and kidney function may need to be monitored. https://www.petcoach.co/canigive/dog/aleve/