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Updated on September 23rd, 2025
Pet's info: Dog | Shih Tzu | Male | neutered | 10 years and 9 months old | 25 lbs
My vet is on vacation but I have a question about the new meds my vet prescribed my dog. My dog takes cyclosporine eyedrops ( 1 drop per eye twice a day) for dry eye. His vet also prescribed Apoquel for his skin allergy because he can no longer take steroids due to being diabetic. Since Cyclosporine and Apoquel taken together have adverse reactions will taking the Apoquel while he is on cyclosporine EYEDROPS be harmful?
2 Answers

Answered By Ana M, DVM
Veterinarian
Published on June 20th, 2018
Answered By Justin Plunk, DVM
Veterinarian
Hi, thanks for using Petco Pet Education Center, formerly Petcoach!
Jersey seems to have quite a few things to deal with. While I can't say for sure, it is likely his Veterinarian has considered the costs and benefits of the simultaneous administration of his medications while prescribing them. The amount of cyclosporine that will be absorbed systemically are likely to be much lower than therapeutic doses of the oral version. Continue administering the medication as prescribed by your veterinarian, and call them at the earliest convenience for clarification. If you notice an issue with Jersey in the mean time such as loss of appetite or lethargy, have him check by a veterinarian immediately.
Hope this helps!
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