My obese cat's bloodwork: Any other health issues to worry about?

Thank you for sending over the copies of Gonzie's blood work! Looking at the provided results, I see that his creatinine is a tiny bit elevated. This value increases with kidney damage or dehydration. I'd certainly recommend talking to his vet about rechecking his kidney function in a month or two, as well as running a urinalysis to see how well his kidneys are working to concentration his urine. The monocyte increase is extremely mild. I don't worry when this type of white blood cell increases a tiny bit while other white blood cell lines (especially the neutrophils and lymphocytes) are normal. Stress alone can trigger this minor elevation. The RDW helps to give the proportions of the red blood cells' size and volume. Again, this minor elevation does not seem to be significant. A 50% hematocrit is slightly elevated, which means that Gonzie has some extra red blood cells. I would much rather see too many red blood cells than too few! His blood volume could also be more concentrated if he's a bit dehydrated. Platelets can be challenging to read on CBCs since they can clump together, so the machine may read a clump of several platelets as just one single cell. In these cases, it's always useful to manually examine a blood smear under the microscope to determine if adequate numbers of platelets are present. Nothing on the provided lab work makes me terribly concerned at this moment, but I do think it's worth tracking his kidney values and confirming an accurate platelet count. I hope that everything goes well for Gonzie!

Hi there. Based on these lab results, I don't see anything concerning here - it looks like this kitty's liver and kidneys are in good shape, normal blood sugar (so no diabetes), and normal thyroid. The minor changes noted (slightly elevated protein, and slightly elevated eosinophils) do not generally have any major clinical significance. So this wouldn't concern me at all, as long as he seems healthy clinically. It sounds like he's a pretty hefty boy, so I agree that getting him started on a weight loss plan would probably be a good idea! I hope everything works out well for the adoption. :)

From what the blood results are showing your cat is not having any important renal issue at this stage. Hyperthyroidism is well controlled as well. It will be good anyway to keep monitoring renal parameters (Urea and Crea) but adding also the so called SDMA which can indicate early stage renal failure (more sensitive than the other two). I think is a good idea to increase anyway the amount of wet food he is having, and if he likes sardines, of course that is a good option. Hope this answer was helpful, but please do not hesitate to contact us again on the forum or by requesting a consultation if you have any more questions or to discuss it any further.

Kudos to you for being such a diligent owner to your senior kitty! SDMA is technically a more sensitive measure of early kidney disease so the fact that it is still normal is excellent news. You’re right that the BUN and creatinine are borderline high, however mild dehydration can do this too. Therefore, if I see values like that in conjunction with highly concentrated urine and a normal SDMA, I’m not going to do anything except to continue monitoring. If the urine is dilute, there is protein in the urine, etc. then I investigate further. All in all, I agree that there is not much cause for concern but I’d recheck in 3-6 months. Best wishes to you and Tony!

I don’t think this shows renal disease. His creatine is normal with a slightly elevated BUN. To me this is more an indication of mild dehydration than kidney disease. He is slightly anemic also which is not uncommon in senior animals but may indicate a chronic medical problem. The eosinophils are slightly elevated which can be due to allergies or intestinal parasites. Basically for a thirteen year old cat there is nothing here that is overly concerning. Bloodwork is just a moment in time though so if you’re concerned I would repeat it again in a month or two so you can see if there is a trend indicating progression of a medical problem or kidney disease. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for Beau.

Poor guy. I see elevate liver enzymes (ALT,AST) and kidney values on the paperwork you have attached here. Low hgb means that the red blood cells are not oxygenating well, but if the RBC count is also low (anemic) then that is a sign of chronic kidney failure. Cats can recover from kidney disease depending on the underlying cause. An abdominal ultrasound is needed to determine the cause of the kidney failure exactly, or a positive response to bloodwork is used as a means of determining a positive outcome. In most situations we treat the pet with fluid therapy to help idurese (flush out) the harmful toxins (BUN, CREA), get the pet started on a prescription kidney diet (ie. Hill's K/D, Royal Canin Renal) and also a supplement (Azodyl- which helps to remove toxins from the gut) can be given as well. The most concerning values for me on this bloodwork are the liver values (AST, ALT). It is not common for a cat to be in both kidney failure and to have abnormal liver values concurrently. THis raises suspicions for infectious diseases such as any number of tick diseases. I would recommend discussing with your vet about possibly doing a tick panel, if the history indicates tick exposure is probable. Also a FeLV/FIV test may also be indicated, depending on the complete CBC results, which you didn't post here. At the very least a liver protectant medication should be started, which is typically a medicine called Denamarin. Additional treatment may be needed depending on the underlying cause for the liver abnormalities. If you would like to discuss Toby's case further, then please feel free to request a consultatoin with either myself or another expert here. Toby's case is definitely a more complicated case where it is best to have a complete dialogue back and forth to get all the information you need to make the best decision moving forward with his care. I wish you all the best moving forward with Toby's care and I hope that he makes a full and speedy recovery. Take care.

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. Based on these lab results, I would suspect renal disease. BUN, Amylase, magnesium and CPK all can become altered with renal impairment. The weight loss may be due to muscle wastage due to chronic renal disease or something else may be going on. I would consider having Tigger's urine specific gravity checked and also send out an SDMA test to see if the kidney's are the main problem. At 14.5 years of age, renal disease would be high on my list of causes of these symptoms. Other problems such as cancer and inflammatory diseases may be the cause of the symptoms as well. I would recommend having your vet pursue additional testing to get more of a definitive answer on whether or not the kidneys are impaired and if not, coming up with further recommendations on diagnostics and treatment. I hope this helps guide you in the right direction. Please let me know if you have any other questions or concerns and I would be more than happy to help you further.