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Senior cat not eating, losing weight, and has high blood test results.

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Mediumhair | Male | neutered | 14 years and 6 months old | 9 lbs

14 1/2 year old male cat not eating and losing weight. Red flagged blood test results as follows: BUN 44mg/dl, Magnesium 2.8mEq/L, Amylase 2967IU/L, CPK 650IU/lL.

2 Answers

Most Helpful Answer

Daniel Fonza, DVM

Answered By Daniel Fonza, DVM

Veterinarian

Published on March 21st, 2018

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. Based on these lab results, I would suspect renal disease. BUN, Amylase, magnesium and CPK all can become altered with renal impairment. The weight loss may be due to muscle wastage due to chronic renal disease or something else may be going on. I would consider having Tigger's urine specific gravity checked and also send out an SDMA test to see if the kidney's are the main problem. At 14.5 years of age, renal disease would be high on my list of causes of these symptoms. Other problems such as cancer and inflammatory diseases may be the cause of the symptoms as well. I would recommend having your vet pursue additional testing to get more of a definitive answer on whether or not the kidneys are impaired and if not, coming up with further recommendations on diagnostics and treatment. I hope this helps guide you in the right direction. Please let me know if you have any other questions or concerns and I would be more than happy to help you further.
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Related Answers from Veterinarians

  • Answered By Dr. Dayna, DVM, CVA

    Veterinarian, Certified Veterinary Acupuncturist

    I am sorry to hear that Tigger isn’t feeling well. Was a urine run? I would suspect early renal diseas with the elevated BUN and amylase but a urine would confirm. Also high CPK could be heart related so I would make sure murmurs were heard . I would also consider testing for pancreatitis. Best of luck and I hope you find an answer soon. Thank you for using Pet Coach.

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