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My cat has a UTI. Why no antibiotic prescribed with Prednisolone?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 3 years and 5 months old | 11 lbs

My cat has a UTI and my vet prescribed Prednisolone without an antibiotic. Is this normal? I understand wanting the steroid to reduce inflammation but shouldn't we get an antibiotic to actually help fight the infection?

1 Answer

Most Helpful Answer

Andrea M. Brodie, DVM

Answered By Andrea M. Brodie, DVM

Veterinarian

Published on October 22nd, 2018

Yes this is normal. Most urinary tract "infections" in non-geriatric cats are not caused by bacteria (antibiotics kill bacteria) but inflammation caused by stress. This is called Feline Idiopathic Cystitis. So Prednisone does two things: It takes the inflammation whch in turn takes the pain, and it is also a diuretic which helps flush the bladder.
Male cats also seldom have a bacterial cystitis as the urethra is much longer than a female's urethra and therefore bacteria would have to travel much farther to get into the bladder.
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