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Did stopping my cat's prednisolone cause hind leg paralysis?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 3 years old | 13 lbs

Can improper weaning of prednislone 5mg for my cat who was on it for neurological issues for six days cause sudden paralysis of hind legs? I took it upon myself to try to wean him off to avoid another return to the vets. I lost him a week ago and am overcome with extreme guilt and sadness. He was only 3

1 Answer

Most Helpful Answer

Lauren Jones VMD

Answered By Lauren Jones VMD

Veterinarian

Published on September 18th, 2021

First of all, I'm very, very sorry for your loss. Only six days of prednisolone isn't a very long course, as some pets take the medication for months to years - this is when tapering is most important. Discontinuing prednisolone with or without a taper shouldn't lead to hind limb paralysis. Since Parker was so young, one of the most common causes of hind leg paralysis is something called a saddle thrombus (or aortic thromboembolism). This is a blood clot that occurs due to underlying heart disease. While I certainly don't know the cause of Parker's neurologic issues, some acute neurologic problems can arise from blood clots in the brain. Please know that your weaning the prednisolone would not have caused his hind limb paralysis. Again, I'm very sorry for your loss.
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