My cat has seizures, vomiting, weight loss, but blood work is normal.

Thank you for using Petco Pet Education Center, formerly Petcoach! I'm sorry to hear that Clunker has been having seizures. It is important to see exactly what is going on, to determine that he is having a true seizure, as opposed to a collapse or localized tremors for a different reason. A video would be very helpful and I would be happy to provide a consultation. If this is a true seizure, they are usually the result of abnormal brain activity. This can be due to a large number of diseases including brain cancer, infection, or epilepsy (the cause of which is not currently known in cats). With brain cancer or epilepsy, blood work can be normal, however, x-rays or a CT scan would determine if there is something else causing the seizures. It may be helpful to know that seizures themselves are not thought to be painful, and it is normal for animals to urinate/defecate while they are having a seizure. This frequency of seizures is definitely confusing and distressful for Clunker, and a veterinarian can prescribe an anti-seizure medication to keep him comfortable. It is important to have Clunker evaluated by a vet to ensure that there is nothing else that can be causing collapse or tremors, such as a hormonal issue or viral infection, and to have him treated appropriately.

If all his bloodwork was normal that rules out kidney disease, liver disease, diabetes, etc. If your vet did not test for hyperthyroidism than a test should be done. An x-ray and/or ultrasound is defintely needed and will, hopefully, provide more information. He could have an infection, cancer, or obstruction/foreign body to name a few other possibilities. If he is not able to keep food down, I am not sure waiting until Friday is a good idea. He may continue to weaken and may become dehydrated. If your vet can't take an x-ray then you could consider taking him to an emergency clinic or another vet that can. An anti-vomiting injection may be helpfull if your vet didn't give him one. I hope that his problem is diagnosed and treated soon!

Poor Checker! This is a huge amount of weight to have lost in a year, so I would say that something is definitely wrong. In older cats with significant weight loss like this and normal blood work, the most common possible causes would be an intestinal absorption issue like inflammatory bowel disease (which can be present even if she is not having diarrhea), or some type of abdominal cancer. The next diagnostic steps would be abdominal x-rays and ultrasound, with exploratory surgery and intestinal biopsies if needed to get a definite diagnosis. If this isn't possible for financial reasons, a trial course of oral steroids and injectable vitamin B12 might be helpful - I would suggest discussing these options with your vet to see what he/she recommends.

He could have this behavior from an ear infection, head injury, low blood sugar or epilepsy. If Sherlock is back to normal then it was a seizure, if he's still having these problems and the blood work was normal I'm concerned about a serious neurological problem. I would take him back for a recheck if he's not much by tomorrow. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for Sherlock.

I'm sorry to hear that Maci is having this problem! Idiopathic epilepsy, which refers to seizures without any underlying cause, is rare in cats but can occur. Other possible causes would include a brain tumor or neurologic disease of some kind, as there would not be any evidence of these issues on normal bloodwork. If you are concerned and want to try and get a definitive diagnosis, you can request referral to a veterinary neurologist for further testing, which would likely include an MRI or CT scan of the brain as well as a CSF (cerebrospinal fluid) tap. If going to see a specialist is not an option for you, your veterinarian should still be able to prescribe medication to control Maci's seizures even without knowing what the underlying cause might be - I would definitely recommend this at this point, if she is having seizures every other day.

Poor Sachi! Significant weight loss and inappetence are certainly a major concern. I'm glad to hear that his blood work (I assume a CBC, chemistry and T4?) was unremarkable. However, foreign body intestinal obstruction/blockages, intestinal malabsorption issues that can cause inflammatory bowel disease (IBD) or exocrine pancreatic insufficiency (EPI), chronic pancreatitis, or cancerous processes, do not necessarily cause changes on screening blood tests. If Sachi has not yet had abdominal x-rays or an ultrasound, consider talking to your vet about these tests as his next diagnostic step. If he has a foreign body obstructing his intestines, this is a surgical emergency, and these tests would be helpful in obtaining a diagnosis. If pancreatitis, IBD or EPI are more highly suspected, consider talking to your vet about testing for vitamins B12 and folate, as well as TLI and fPLI. I hope this helps!

Thank you for your post! I am sorry to hear Shurbee is not doing well. My concern at this age would be some type of malignancy. In older cats, one of the more common things we see in regards to cancer is intestinal / GI lymphoma. This does not always show up on blood work. I would highly recommend Shurbee get an abdominal ultrasound as the next diagnostic step. Hope this helps and feel free to contact me with any further questions / concerns