My cat on Prednisone has excess thirst and urination. Is it the meds?

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Danny. I'm sorry he has hives. Excessive drinking and urination are common side effects of prednisone, so this is to be expected. Once he has finished his course of prednisone, the side effects should go away. I hope this helps!

Cats are normally very resistant to the side effects of Prednisone, so the signs you are describing are very usual to see in cats. Was Elliot started on any other medications that may be causing these symptoms? I would definitely discuss any changes in his Prednisone dosing with his veterinarian. Sometimes we can get away with lower doses, but need to decrease the amounts carefully. We normally do not recommend decreasing the amount by more than 50% at a time, so decreasing from 1 mL twice daily to 0.5 mL once daily would be decreasing the dose by four times, which might be too extreme for Elliot (even after only 6 days on the steroid). The good news is that we do not tend to see heart problems with oral steroids (only injectible steroids), so you do not need to worry about heart problems with oral steroids. I hope that answered your question. Thanks for using Petco Pet Education Center, formerly Petcoach.

I recommend to have Rocky examined by his veterinarian. Prednisone can cause suppression of the immune system and could allow a urinary tract infection to set in. It is best to get this checked out quickly. Also, there are other methods to help cats with arthritis. Some pets do require steroids but you may try supplements and other pain medications first since steroids tend to carry more side effects. There is a supplement called Adequan that many cats do very well on. There is a medication called Gabapentin that works well for arthritis. Starting an omega-3 fatty acid supplement for pets can also be beneficial. Most pets benefit from a combination of treatment. I hope this helps.

Thanks for using Petco Pet Education Center, formerly Petcoach! Being tired and thirsty can be linked to the prednisone. Prednisone specifically should not be discontinued abruptly and needs to be tapered slowly. The tapering of the prednisone has to be done carefully and calculated based on the weight of the patient. I recommend you check in with your veterinarian who prescribed the prednisone for the tapering schedule for it as they have all the information they need for this. They can also advice on the other medication. Best of luck!

Steroids interfere with antiduretic hormone which normally is responsible for resorbing water in the kidneys. Thus more water is lost in the urine making it much more dilute. This is likely why you are getting low readings for usg. If you are still concerned you could have your vet run an SDMA check on blood for early signs of kidney problems

If he was on 12mg of prednisolone for 10 days straight and then it was suddenly stopped, then yes that could be part of the problem, but its also possible that he is still ill from the original disease. I would strongly recommend that you take to your veterinarian; it would be useful to recheck a physical exam and some blood tests. They may recommend running a baseline cortisol to ensure that stopping the pred is not the cause of current symptoms. Thank you for asking Petco Pet Education Center, formerly Petcoach!

You are correct that these are very common side effects of prednisolone. The good news is, they are normally not dangerous to the dog - just a bit annoying to deal with. Without knowing why Snitch was prescribed this medication, I can't tell you whether or not it would be safe to skip a dose - so I would not recommend making any changes to his prescribed medication schedule until you speak to his regular veterinarian. I would suggest calling his veterinarian to discuss your concerns and ask about possibly modifying his dose when you are able to - until then, it would be best to continue the medication as prescribed.