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At Petco, learn more about the benefits & differences of Interceptor & Interceptor Plus dewormer for dogs with heartworm, roundworms, hookworms & tapeworms.
Updated on October 23rd, 2025
Search Petco to find the benefits of both Interceptor and Heartgard worm medicines for dogs. We strive to help you keep your pup happy and healthy.
Updated on October 23rd, 2025

Discover how to choose the best supplements for your pet’s health, from essential vitamins to joint support and digestion aids. Learn age-specific and seasonal supplement tips for cats and dogs.
Updated on October 23rd, 2025
Learn how to care for your dog, recommended diet and training. Find the right food, supplies and equipment at your neighborhood Petco.
Updated on March 5th, 2026
Learn about the benefits of fish oil for dogs. Order online from Petco and save with Repeat Delivery or Curbside Pickup.
Updated on October 23rd, 2025
[Advantage II](https://www.petco.com/shop/en/petcostore/brand/advantage?utm_source=PetCoach&utm_medium=questions&utm_campaign=bayeradvantage) flea prevention is applied to your dog topically, spreading over the skin and hair. It kills fleas through contact, which means that fleas don't have to bite your dog to be exposed to the preventive. On the other hand, with oral flea medications, fleas are killed only after biting your dog and ingesting the medication. One flea bite can lead to an allergic reaction in sensitive dogs. Additionally, some oral flea preventives last as long as 12 weeks. Pet parents may find this more convenient. Most topicals must be applied every 4 weeks. Regardless, either product must be applied or administered regularly and following label directions in order for it to be effective.
Updated on September 24th, 2025
I would recommend to alternate between two different type of flea product every 14 days. Some give advantage then 14 days later give another product then repeat the advantage another 14 days later and so on. I would try an oral flea preventative like comfortis (as long as no history of seizure and not currently on ivermectin for mange treatment) or nexgard. you can talk to your vet about other types of flea preventive too that they recommend if they don’t carry these. Also make sure you treat the house and yard for fleas as fleas live in the environment not on the dog. I hope this helps!
Updated on September 24th, 2025
Advantage works well for some areas of the US and some pets. If you are still finding fleas on Lucky in a week or two, you may need to try a prescription product sold by your vet. It can take 3 months or more of consistently treating the pets in a household and the home to get fleas under control.
Updated on September 24th, 2025
Great question! Because 15 days have passed, it's fine to give Roman the Advantage II. I would also give him Capstar. It's a one time pill that is safe to give now and will start killing fleas in 30 minutes. Remember as well you need to disinfect the environment, as the environment can be a continuing source of fleas. Wash his bedding in hot soapy water, and vacuum the furniture and carpet surfaces. You can use a spray to kill fleas in the house, such as Indorex, or a flea bomb would work well to kill the fleas in the home. I hope this helps :-)
Updated on September 24th, 2025
You really should only need one or the other product. Putting both products on at the same is not recommended. If you are using Advantix II and you are still seeing fleas then I suggest you switch to another flea prevention.
Updated on September 24th, 2025