Thanks for reaching out about Sprou and including pictures. By the history and pictures, the most likely answer is a dermal (sebaceous) cyst. This condition is very common in middle aged guinea pigs. Keeping it clean as you did, is a good start. Clipping the hair around the edges to prevent further contamination is important. Ideally a veterinarian should be seen to have the cyst surgically removed, else it is likely to come back, over and over. Secondary infections of the open wound are also possible. Good luck.