Why are my new pythons aggressive and not eating in their new home?

It may be a combination of being in a small cage and a new environment. Ball pythons are notorious for not eating if stressed. Make sure the temperature is correct also. A cold snake will not eat. Wait a few days, then offer a pinkie at dusk of in the evening. Gently tap her nose to elicit a strike. Cover the cage for more privacy/security. You can also try scenting the pinkie with some used gerbil bedding. Ask the local pet store if you can have some from the gerbil cages.

I suggest you just not feed her for a few weeks and then try again. Her lack of appetite may be due to shedding. Reptiles can not eat for months and still be fine. It is not ideal for them to go quite that long though. So, wait a few weeks, try again with frozen-thawed and see what happens. You are welcome to post again if she doesn't eat and we can see if we can help you better. Be sure he cage temperature is correct. If they are too cold they often won't eat. Basking spot temperature should be 88 to 96 degrees Fahrenheit and an ambient temperature of 78 to 80 degrees. The ambient temperature should not fall below 75 degrees.

Ball pythons are typical not very aggressive unless it is a female protecting her eggs. Also, juveniles can be a bit mouthy but they typically outgrow it with regular handling and as they mature. Reedus may be stressed. Survey the area in and around the enclosure for any negative stimuli. This may include loud noises, strong vibrations, bright lights or high traffic. Reduce or eliminate any if found. Provide a hide on each side of the enclosure. If Reedus will allow, handle him/her for ever increasing periods of time. You can place a small article of your clothing in the enclosure to get him/her used to your scent. If the behavior persists, consider an exam with your veterinarian or a vet experienced in treating reptiles to diagnose illness or injury. Either can cause a sudden change in behavior.

Consider bumping him up to a juvenile rat (or small adult) once a week. An exam with an experienced herp veterinarian would also be recommended to diagnose illness or injury. Frequently, either may result in behavioral changes or sudden aggression.

Thanks for reaching out about your ball python. Seems like your husbandry is good. Intestinal parasites are common in snakes, more prominent in recent acquisitions. A fecal examination by a veterinarian is probably the first idea. Metabolic disorders or systemic infections are other possibilities. Good luck.

Let him adjust to the new environment for 3-5 days. Do not handle him during this time. After several days, gradually introduce your hand into the enclosure for ever increasing periods of time. As he acclimated to you, you can handle him for shortly periods of time initially. Increase the time as he becomes comfortable but be aware that he can get chilled if not returned to the warm cage.

Thanks for reaching out about the snakes. Breeding season can be an explanation for not eating, but these animals remain very active and alert. If lethargic, weak or quiet, a veterinary visit is recommended to assess and provide a diagnostic/treatment plan. Being together, intestinal parasites would be a plausible explanation also. Good luck.