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Updated on September 23rd, 2025
Pet's info: Dog | Mixed Breed Medium (23 - 60lb) | Female | spayed | 15 years and 7 months old | 57 lbs
Have a 16 yr old female mix Australian Sheperd. Had severe UTI in Jan that required a month of very expensive antibiotics. She has started smelling bad again for about 3 days. Have some cephalexin from a skin infection. She also takes other meds. Was wondering if anything she takes now would interact with the cephalexin? She takes Apoquel 8 mg a day, Thyro tab 0.4 mg 2x day. Metacam 7.5 1/4 tab a day. Enacard 10 mg a day.
2 Answers

Answered By Lauren Jones VMD
Veterinarian
Published on April 27th, 2017
Answered By C. Rathjens, DVM
Veterinarian
Sounds like Katie has a lot of medical issues going on.
I would not recommend giving the cephalexin, particularly since she had a recent infection that required a month of antibiotics. Cephalexin is a first line antibiotic at best, and it sounds like Katie needs something stronger. If you give her the cephalexin, you may end up killing weak bacteria in her urine and promoting the overgrowth of resistant bugs. The cephalexin won't interact with her other medication, but it could make her overall health situation worse.
I recommend checking in with your veterinarian again to make sure she really has a UTI or skin infection, have them determine if cephalexin is appropriate for the infection. It will save you money in the long run to get the right thing from the start.
Best of luck!
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