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Can I save leftover Frontline Plus if I bought the wrong size for my dog?

Updated on September 23rd, 2025

I bought my dog the Frontline Plus for a 89-220 pound dog, but he is only 35 pounds. Can I put it in a vial and save what I do not use?

1 Answer

Most Helpful Answer

Answered By Debi Matlack

Veterinary Technician

Published on April 23rd, 2015

Ideally, you should return the product and exchange it for the appropriate size based on your dog's current weight.
Manufacturer's packaging protects the product from 2 important things: light and air. Drugs and insecticides can be destroyed and rendered ineffective if mishandled. Keep in the syringe, expel all bubbles, and store in a cool, dark place. Refrigeration is ideal, but under the sink or other ‘chemical repository’ is ok. Airtight tupperware is best as some of these insecticides are volatile. Revolution is very volatile and must be stored chilled once packaging is breached. Do not freeze.

Frontline Plus (Fipronil & (s)-methoprene), use the following guidelines:

The dose is 0.0305ml/pound. Multiply 0.0305 times your pet’s weight for dose

(package instructions)

Dogs 11-22 pounds - 0.67ml 0.6ml for 20lbs 0.75 for 25lbs

Dogs 23-44 pounds - 1.34ml 0.9ml for 30lbs 1.5 for 50 lbs

Dogs 45-88 pounds - 2.68ml 1.8ml for 60lbs 2.68 for 88lbs

Dogs 89-132 pounds - 4.0ml 2.7ml for 90lbs 4.0 for 133lbs

63Pet Parents found this answer helpful

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