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My puppy is tired and biting after metronidazole. Is this normal?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed | Female | unspayed | 2 months and 1 day old | 5 lbs

We took our puppy to the vet and they gave her metronidazole and a few hours after her first dose she has a loss of energy is and she wants to bite almost everything is that normal

1 Answer

Most Helpful Answer

Destini R. Holloway, DVM

Answered By Destini R. Holloway, DVM

Veterinarian

Published on July 7th, 2017

Lethargy (loss of energy) following a dose of metronidazloe is a sign of a possible drug reaction. Her biting everything could be a sign of discomfort? This is quite an unusual symptom, so it is hard to say for sure. Most of the time a reaction to Metronidazole involves any of the following: neurological symptoms (i.e. seizure, head tilt, etc), stomach upset (vomiting and or diarrhea) and lethargy.
I would suggests calling your vet in the morning to ask if the medication should be continued. They likely will have you stop the medication and try an alternative one. Also, I would make sure you are giving this medication with a full meal, to reduce adverse reactions. I hope that everything works out well for your pet Daisy. Best wishes and take care.
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