Why does my 2-week-old puppy have pus-filled bumps on his belly?
It looks like you've done a lot to help this little guy. I'm sure the vet would have told you this, but make sure you are stimulating him to poop after each feeding by wiping his bum with a warm, moist, tissue or soft cloth. Below is a link to an article with great information about caring for newborns.
https://vcahospitals.com/know-your-pet/puppy-orphaned
These little pus-filled bumps are due to a bacterial infection (pyoderma). Puppies commonly get this on their bellies and they usually go away with good cleaning.
I recommend cleaning the belly with a medicated wipe or shampoo (can get this at the pet store) once a day until the bump(s) are gone. If it seems to get worse, then you'll want to take him into the vet for an exam. Below is a link to an article with more information about pyoderma.
https://vcahospitals.com/know-your-pet/pyoderma-in-dogs
I hope that helps and your pup gets better soon.
Updated on September 23rd, 2025