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My limping dog hates car rides. How to make a long vet trip easier?

Updated on September 23rd, 2025

Pet's info: Dog | Great Pyrenees | Female | spayed | 7 years and 1 month old | 120 lbs

Our 6 year old female Great Pyrenees is a family pet who also loves to patrol our farm home’s acre fenced yard. She has a buddy we rescued after her Pyr friend died from tragically being over sedated at the local vet. Missy has begun limping some favoring her right rear leg but runs on it. I need advice on how to help her travel 90 minutes away to a vet clinic where she will get the best diagnostic care. She hates to ride in the Suburban. Advice needed to ease her ride.

1 Answer

Most Helpful Answer

Dr. Strydom, DVM

Answered By Dr. Strydom, DVM

Veterinarian

Published on February 7th, 2022

If she is anxious in the vehicle it is best to contain her in a crate. That would be the first consideration.

There are not many over the counter medications you can give that will make her sleepy other than antihistamines (like Benadryl) but even sometimes they do not have that affect on dogs like it does in people. I suggest you try Benadryl at home on day when you are there to see if it actually works. Dogs take a very large dose compared to people so a dog her size would need 5 of the 25mg adult human tablets. If it makes her sleepy then on the day of travel you can give it to her 1-2 hours before you leave for the vet. You can buy the generic Benadryl (diphenhydramine).

Hope this helps. Best wishes.
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