My dog has purple spots on her liver after spay. Is carprofen safe?

Without reviewing the full blood results and changes over time it is very difficult to say for sure but if your dog is unwell (especially with increased thirst, vomiting or diarrhea) and blood results are developing more concerning changes then I would be concerned about continuing with carprofen until a conclusion can be reached as to what is causing the chenges in the blood work. Obviously however, Buddy is in pain and shoudl be receiving some pain relief in order to improve his comfort leveles - you shoud speak to your vet about other types of pain relief or deek referral to a specialist

Carprofen is an nonsteroidal antiinflammatory medication (NSAID) like aspirin or ibuprofen for humans. It's used daily for arthritis or other chronic pain, and short term for more acute/temporary pain. The half life is the amount of time it takes for half of the drug to leave the body (via the liver, kidneys/bladder, or gut). Carprofen can occasionally have side effects on the liver, so if he's going to be on it long term, it's usually recommended to check liver values after 2 weeks. That said, liver issues are rare. Intestinal upset (vomiting/diarrhea) are also possible side effects and if he had any of that you'd want to stop and figure out a different appropriate medication with his vet. With just 6 days of medication, no additional testing will be done. You can (and should, if that is how it was prescribed) give carporfen daily. Appropriate supplements could include fish oils and glucosamine and others, depending on what exactly is going on. I'd recommend asking about supplements for long term when you go for your recheck visit

Accidents happen! Fortunately, the carprofen won't impact her heart disease or interact with the pimobendan. However, there is a chance that she could experience some stomach upset with vomiting and/or diarrhea, particularly since this is a pretty big dose for a dog her size. With this kind of dose, the worst case I'd expect to see could be ulceration of the GI tract. Normally, carprofen is prescribed at a dose of 4.4 mg/kg over 24 hours. Today, your dog consumed 7.86 mg/kg. In most cases, we don't see toxicity impacting the kidneys until a dose of 40 mg/kg is ingested. With all of that in mind, your dog should be absolutely fine! In order to be extra cautious, I'd recommend feeding her a bland diet of boiled white meat chicken and white rice for a few days, then gradually mix it in with her normal food over 5-7 days. You can also call your vet to see if they can give a dose for an antacid, like Pepcid. (It's illegal for me to do so without having examined your dog.) If you see any vomiting, diarrhea, lethargy, or blood in the stool, you should call your vet right away. I hope that everything goes well!

I wouldn’t recommend it -carprofen may not be safe for dogs that have underlying medical conditions like a sensitive stomach, kidney or liver disease. Older dogs are more likely to have an issue like this. If Goose was prescribed carprofen in the recent past it might be a little safer but otherwise I’d recommend talking to your vet first. Sadly there is not another over the counter pain option that I’d consider to be safer so if you feel he’s in significant pain you may want to consider seeing a vet tonight.

Hello. Spaying is a very good idea, but in all probability, the nodules on the liver will not be touched. Those liver values are a concern, and I would possibly look more into what is going on with the liver before putting Dahlia under general anesthesia. I assume an ultrasound of her abdomen was done & this is how the cyst & nodules were found. Have chest x-rays been done? In case the liver nodules are cancerous, we want to make sure her lungs are clear of any metastatic lesions. Also, if the cyst on her ovary is not bothering her & she is not having any reproductive problems, spaying her may not be advised either until your veterinarian can get her liver numbers down. We do have supplements that may help the liver to heal. Follow your veterinarian's recommendations for any follow up testing & treatments. Good luck & thanks for contacting Petco Pet Education Center, formerly Petcoach.

Thank you for submitting your question regarding Penelope. It is good that her ultrasound came back normal. I typically recommend blood work such as a bile acids panel (liver function test) and even a coagulation panel prior to surgery in the case of elevated liver values. These blood panels will help to ensure that it is safe for her to go under anesthesia. I hope this information helps!

Hi there. Yes, that should be okay - Trifexis doesn't have any harmful interactions with those meds. The only possible issue I can see is that all three of them have stomach upset as a potential side effect, so if your girl has a sensitive stomach or has a history of vomiting when you give the Trifexis, then it may be better to wait until she's finished with her current meds to give it. But if not, it should be fine to go ahead and give it today if you want to. :)