Dog on prednisone: How to safely taper off when vet is unresponsive?

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. 30mg of prednisone is a high dose for Ozzy. I would suggest to taper it down slower. There are different protocols to do it and decreasing slowly the dose on weekly basis is probably the most frequently used protocol (for example 20mg every other day for a week then 10mg every other day for a week etc). Another benefit of tapering will be better monitoring of potential relapse of strangles. Sometimes once we reduce the dose of steroids, the skin gets worse, so we can up the dose of prednisone quickly. Please, get in touch with your vet to confirm the protocol of tapering down the dose of prednisone. Good luck.

Sorry to hear about the side effects the Prednisone has been having on Hachi. It certainly can be a drug that, while it has its place, can be difficult for animals to handle on a daily basis. Before beginning a taper, I would speak to your vet about the side effects of the drugs. Depending on the purpose of the prednisone, it could be very important to keep Hachi on the drug for a little longer. Another factor that will play into the tapering period is how long Hachi has been on the drug. If he has only been on the drug for less than 5-7 days, a very short taper would be required. However, if he has been on it for any longer than one week, the drug should typically be tapered off over several weeks. At 50mg twice daily, I would start by cutting it to 25mg twice daily for 7-10d, then 25mg once daily for 7-10d, then 12.5mg once daily for 7days, then 12.5mg one daily every other day for 7-10d, then discontinue. However, please consult with your primary vet before pursuing this, as he may have options for you including additional drugs that can help prevent some of the side effects you might be seeing. If you want to talk some more in detail about what is going on, let us know and we can set up a consultation for you regarding Hachi's health.

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Dozer. I'm sorry he has cancer! Do not suddenly take him off the steroids, you should work with the local vet to taper him off of them if you do not want him to be on them. Give them a call to discuss a schedule to taper them off. I hope this helps!

Your dog should be weaned off Prednisone slowly. In many ways, prednisone is similar to the corticosteroid hormones cortisol and aldosterone produced by the adrenal glands located along each kidney. Because of this, when taking prednisone, the adrenal glands start decreasing their production of cortisol. It would be too shocking for the adrenal glands to find themselves out of the blue in need of producing cortisol in large amounts again, so by tapering the prednisone gradually, the glands are given some time to resume their normal function. The main risk is what is called an " addisonian crisis" or "iatrogenic hypoadrenocorticism" which can be life threatening and can cause the dog to go into shock. This can happen when the prednisone is stopped out of the blue and the adrenal glands are dormant because they weren't given a chance to gradually become active again. When this happens, the dog's potassium and sodium levels get unbalanced. The sodium levels start to fall, while the potassium levels start to rise. High potassium levels can have a detrimental effect on the heart and can lead to circulatory collapse. Affected dogs may appear weak, lethargic, they may vomit, have a low, irregular heart rate and may go into shock and even collapse. Affected dogs need to seek immediate emergency treatment to correct the electrolyte imbalances and possible low glucose levels through supportive care consisting of fluid therapy and careful monitoring. Rapidly-acting corticosteroid medications such as prednisolone sodium succinate or dexamethasone sodium phosphate may be needed. This whole ordeal can be easily prevented by gradually tapering the dog off the steroids. Dogs on prednisone for quite some time, need to be tapered even more gradually. The vet will tell owners how.

I believe I provided you with the answer to this question before regarding the tapering. Now that I know that he is being treated for MCT, I would recommend speaking to your vet regarding the treatment. Prednisone is not generally considering the gold standard treatment for this condition. If he has not offered you a referral to an oncologist, I would request one if you are looking to pursue any other therapies. One of the best therapies available right now for Mast Cell Tumors is a drug called Palladia. I would love to consult with you concerning Hachi's condition including this drug and a possible tapering schedule if you were not clear on the answer I provided you earlier. Just let me know or one of the other experts here so we can try and find a way to make Hachi more comfortable.

STeroids should be decreased gradually. After about 5 days of this treatment with 12 hours dose, you can decrease it to 5 every 24hours with food for 5 days then 5 mg every other day for other 5 times (10days) and then 2.5 mg every other day for 5 times. At the end of this you can stop it. I would recommend to stop methocarbamol gradually but after another check up at your local vet, so they can give you precise instructions on how to do it.

Hello, thank you for your question about Romeo. Since the course of the prednisone was very short it is often not necessary to taper the medication. Based on the information that I have found about DermaVet I believe it is safe to use both at the same time. Of course if you notice Romeo develops any symptoms such as decreased appetite, vomiting, or diarrhea I would recommend having him rechecked by your veterinarian. Hope this helps, glad to hear he is feeling better!