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My dog is on Norco. Why frequent bloodwork? Is it drug testing?

Updated on September 23rd, 2025

Pet's info: Dog | Mixed Breed Large (61lb +) | Male | neutered | 10 years and 5 months old | 82 lbs

Our vet started our dog on Norco and said he will have to come in every 3 months for visit and bloodwork, they didn’t explain what type of bloodwork. I’m a nurse and was wondering if this was drug testing like in humans? Do dog metabolize drugs like humans??

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on April 2nd, 2023

Hello. Norco is hydrocodone, a semisynthetic opioid derived from codeine & a DEA Schedule II narcotic. In most instances, dogs do metabolize drugs like we do, but there are some differences. In the case of the Norco, because this is a drug with the potential for abuse, this may be why your vet wants to do blood work quarterly. They are not testing for actual drug levels, like we might do with phenobarbital, but more to make sure Midnight's health remains well. Personally, I only do blood work every 6 months in my patients. Perhaps after a few checks, your veterinarian will consent to twice yearly check ups. You can always ask about this. Thanks for contacting Petco Pet Education Center, formerly Petcoach.
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