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My epileptic dog missed a dose. Why are his seizures increasing?

Updated on September 23rd, 2025

Pet's info: Dog | Miniature Poodle | Male | neutered | 15 lbs

My dog Papo has idiopathic epilepsy and had them under control for 3 mths. On May 3rd at 6 am I administered his pill and come find out he spit it out that morning and didnt take it into 11 am when I found it. I had coated it in peanut butter. Since then he had one seizure on May 5th at 530 am lasting 2 min and one at 745 pm again lasting 2 min. Could it be due to the last dose 4 days ago. He take 15 mgs of phenobarbital at 530 am and 15 mgs of phenobarbital at 530 pm daily.

1 Answer

Most Helpful Answer

Ana M, DVM

Answered By Ana M, DVM

Veterinarian

Published on May 7th, 2018

Thank you for submitting your question regarding Papo. The increase in seizure frequency could be due to the slight medication change you described. However, seizures are unpredictable and this may have occurred even if you had administered the medication on his normal 12 hour schedule. If he has any more seizures, I would recommend blood work to check his phenobarbital level. He may require a dose adjustment. I hope this information helps!
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