My dog had low-grade mast cell tumors removed. What's next?

Thank you for submitting your question regarding Twix. Mast cell tumors are one of the most common forms of skin cancer in dogs. If the margins were clean (meaning all of the cancerous cells were removed), then the mass should not recur. However, mast cell tumors are one of the more unpredictable types of cancer. I recommend closely monitoring his incision site at home for any regrowth. It is best to see his veterinarian at least every 6 months for an examination. At this visit a thorough physical examination will be performed to search for other masses or enlarged lymph nodes. Blood work should be monitored as well. Unfortunately, there is nothing that you or your veterinarian can do to prevent further growths from forming. If any new new growth is observed, a fine needle aspirate should be performed as soon as possible to determine the type of mass. If it requires surgical removal, it is always best to have it done while small for the best chance of achieving clean margins. I hope this information helps!

Since both the tumors were low grade and have not yet metastasized there is no indication to worry about an abbreviated life span at this time. Since your dog is so young and has already had 2 MCTs he will likely have more pop up in the future. It's important to have any little lump or bump you find on him to be checked out by your vet. The sooner they are removed, the less likely they are to spread.

It's a bit of a tough call, but I can see 2 potential options. You could have your vet take the tumor with conservative margins - i.e. leave enough to keep the penis covered - then biopsy that in order to get the grade of the tumor, so that you know what you're dealing with. After that, you might elect chemotherapy, or as you say simply monitor the site, since many are low grade. Your other option would be to consider a course of Palladia, which is a chemotherapeutic drug that is often used in mast cell tumors. It can significantly shrink them, so that they are easier to remove with margins.

I’m sorry to hear about Tsunami’s diagnosis. MCTs are quite common in dogs, and unfortunately due to the cell distribution around the primary tumor, incomplete margins are common. If you want to be confident you’re pursuing the best options for the best prognosis, I recommend asking your vet for an oncologist referral. A veterinary oncologist will be the best specialist to be able to present all the options and their given pros & cons, and they have access to chemo medications that most primary vets don’t carry. If you choose not to pursue referral, then I recommend reaching out to your vet again to discuss the next step. If this were my case, I would probably recommend sampling Tsunami’s lymph nodes with a needle to look for evidence of regional metastasis, and based on those findings discuss if a second surgery is appropriate. Hope this helps!

I'm very sorry Daisy has so many tumors! The course of treatment depends on the grade of the mast cell tumors (MCT). In low grade tumors that have been removed with adequate margins, further treatment is typically not needed. If there is spread to local lymph nodes, for example, then addition treatment is needed. Once the grade of the tumors is known, that will help your decision, but given that you think she might be at stage 3, I would recommend doing surgery and chemotherapy. As for holistic treatments, there may be complimentary treatments you can do in addition to the surgery and chemo, such as acupuncture, and I would discuss the use those with your vet.

A) The likelihood of reoccurrence is higher if the margins are dirty. While it may be categorized as a low grade, it would be helpful to know the mitotic index which is a quantitative measure of mitotic figures observed in the cancer cells. If the mitotic index is high, reoccurrence is more likely. B) If no further treatment is pursued, it may or may not return. C) Prior to any further surgery or treatment you need to have Barney evaluated by a veterinary oncologist to discuss the best treatment options for him.

Hello I would check with your veterinarian about doing xrays to see if there is any evidence of spread to her lungs. Also discuss with your veterinarian if all of the mass was removed ("clean margins") or if additional surgery is needed. In some cases if there is no spread of the cancer and it was completely removed do further treatment is needed.