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Why does my Cavalier with IMHA on prednisone have severe skin sores?

Updated on September 23rd, 2025

Pet's info: Dog | Cavalier King Charles Spaniel | Female | spayed | 6 years and 9 months old | 18.5 lbs

My caveleir King Charles has IMHA for 5 months. She is down to 2.5 mg of prednisone once daily & atopic 25 mg twice daily. Her HCT numbers have gone up but she has terrible ulcer like sores on her face & other areas with hair loss that we thought the prednisone caused. They have gottten much worse, maybe cushions or lymphoma causing it? Could it be a allergy reaction to atopica or a newly partial raw diet? We are days away from euthanizing her because of the extreme sores..help?

1 Answer

Most Helpful Answer

Lindsey Edwards MVB, BSc, IVCA

Answered By Lindsey Edwards MVB, BSc, IVCA

Veterinarian

Published on April 28th, 2018

These do look very painful and yes, euthanasia is a definite consideration given the fact that the treatment she requires for IMHA may be directly or indirectly related to these painful, open sores. A scraping or biopsy of the lesions may help to provide some indication as the the underlying nature of the skin condition and a biochem tests to check for liver disease which can also be linked to such skin issues could be performed but even after a full diagnosis is reached, management options may be limited. If it is a hypersensitivity reaction to medications, referral to an internist may provide alternative treatment regimens for IMHA which may provide some relief
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