Heartworm treatment: dog drooling, weak, not drinking. Is this normal?
Those symptoms can be normal the first day after such an intense treatment with Immiticide and also with Tramadol. The side effects that can be seen with Tramadol are as follows: "Tramadol appears to be well tolerated in dogs. Potentially, it could cause a variety of adverse effects associated with its pharmacologic actions, including: CNS effects (excessive sedation, agitation, anxiety, tremor, dizziness), or GI effects (inappetence, vomiting, constipation to diarrhea)."
With that said, I would still opt to get Clementine examined by a vet soon, especially if her gait continues to be affected and if she isn't drinking water and having normal urinations. Her gums should always look pink, and her breathing should be normal (not panting). I hope that your pet Clementine is able to recover well from her rough 1st day of heartworm treatment. Best wishes and take care.
Updated on September 23rd, 2025