My dog with heart failure took double Spironolactone. Is she safe?

A single dose (not overdosed) should not cause any harm if your dog is fit and healthy. Monitor him for the day, he may feel weaker than normal and urinate more. Make sure water is available all the time.

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Harper. The dose she ate is actually below what the recommended dose would be for a dog her weight, so there is no risk of overdose. This single, low dose should not be a problem. Just don't let her get any more. I hope this helps!

This medication contains a combination of Spinosad and Milbemycin. Milbemycin can be used safely in dogs for heartworm prevention but has other uses as well, and can be given at a dose two to four times the normal dose that we use for heartworm prevention, so I would not worry at all about a higher then normal dose of that medication. Spinosad is used for flea prevention and is a relatively safe drug. The most common side effects seen with its use include a decreased appetite, vomiting, diarrhea, lethargy and rarely, in dogs with a low seizure threshold, possible seizures. Studies on research dogs showed no long term effects on dogs that were given TEN times the recommended dose. Side effects that were seen at that high dose included nausea, vomiting, a decrease in appetite and some diarrhea. She will probably be OK but all you can do at this stage is monitor her for any signs of toxicity. If any are noticed she needs to see a vet immediately.

No, mixing up these medications is unlikely to have any adverse events (other than possible mild gastrointestinal issues as with starting many medications). These medications are quite similar and indeed both have been used for treatment of both conditions. I would continue with their normal prescribed medications when their next dose is due

HI, thanks for using Petco Pet Education Center, formerly Petcoach! I would need to know the milligrams (mg), how many tablets of each and how often he receives the medications to be 100% sure. But he likely will be fine! If he receives any of these medications twice daily just skip tonight's dose. Even if they are just once a day medications he will likely be fine. Call your Vet tomorrow to discuss it with them. I hope this helps and have a good day!

Thanks for using Petco Pet Education Center, formerly Petcoach! If you meant a 12.5mg tablet of furosemide, he should be ok as long as he does not have underlying kidney disease. He will be more thirsty and will urinate more for the next 24-48 hours. Best of luck!

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. Sildenafil is safe to use in dogs with kidney failure. This will help manage the hypertension. If the hypertension is not managed, the hypertension will damage the kidneys further. I hope this helps! Please let me know if you have any other questions or concerns and I would be more than happy to help you further.