My dog accidentally took Deramaxx twice. Is he going to be okay?

Hi there! Since Primo is 84 pounds (about 38 kilograms), 150 mg of Deramaxx would be a dose of about 4 mg/kg. This is within the approved label dosing range for this medication for short-term use, so it's unlikely that you will see any serious side effects related to this - especially since you were able to make him vomit within about an hour, so he probably vomited up at least part of the medication before it was fully absorbed. With any higher-than-normal dose of Deramaxx, it's always possible to see GI issues such as stomach upset or even gastric ulcers - so I would recommend monitoring Primo closely for the next few days to make sure that he's acting normal. If he has repeated episodes of vomiting (more than once or twice), doesn't want to eat, or begins acting lethargic, then I would recommend taking him to the vet right away to be checked out. If he normally takes Deramaxx daily, I would also recommend calling your regular vet in the morning to let them know that this happened - they may recommend skipping his normal dose for the next day or two to help minimize the risk of any problems.

Hi and thanks for posting. I wouldn’t worry too much about this. Griffen consumed more towards the maximum dosage of this medication (4mg per kg of body weight) but he should be ok as long as he is not on any similar medications. He may have some gastrointestinal discomfort such as vomiting and diarrhea as a side effect of the medication. If he is on any similar medications, I would be sure and let us know so we can advise further. I hope this helps!

Normally, a one-time double dose of Rimadyl will not cause any serious problems - but if you're concerned, you can always call the vet who prescribed the medication to ask they want you to bring Rocky in. If Rocky has any vomiting over the next 2-3 days, acts lethargic or doesn't want to eat, then I would recommend having him checked by a vet.

I can understand your concerns. Deramaxx, just like any other pet formulated NSAID, has the potential to cause adverse reactions in dogs. There is no medicine for suspected osteoarthritis that is considered 100% free of possible side effects in dogs. With that said, you should be informed on the potential side effects and what symptoms to watch out for that could indicate there is a problem, such as vomiting, lethargy, decreased appetite, loose stool with or without blood, and to notify your vet if any are seen. For long term use, it is advised to have baseline bloodwork done on your pet to rule out any underlying kidney or liver problems as well. And if your pets history of health is unclear or unknown to your vet, bloodwork should even be considered before the first dose is given. But pets are prescribed this medicine all the time with little to no side effects; although that perspective can be skewed when owners only list the bad outcomes via the internet. However if you do see unwanted side effects it’s recommended to notify your vet immediately and stop the medication. However, there is a good chance he will do well. Best wishes and take care.

You are correct that drugs like Deramaxx should not be given currently with steroids because of the risk of GI ulceration. There should also be a wash out period after steroid use before starting NSAIDs (like Deramaxx) appropriate in length for the time on the drug. I hope this helps and thank you for using Petco Pet Education Center, formerly Petcoach!

Leave out the next dose and Jane should be ok as Carprofen (the active ingredient of Rovera) can be given in a double dose once daily or one dose every 12 hours. Watch her poop for the next teo or three days, if it is black, stop the Rovera and consult your veterinarian. Should Jane get lethargic, start to vomit or get diarrhea, you should also take her to your vet for an exam and blood work.

There is no contraindication to giving Deramaxx and diphenhydramine (Benadryl) together. Dogs on Deramaxx should avoid any other non-steroidal anti inflammatory pain medications, corticosteroids like prednisone, and aspirin.