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Mixing puppy Benadryl & skin meds? Can I increase dose for hyperness?

Updated on September 23rd, 2025

Pet's info: Dog | Pembroke Welsh Corgi | Female | spayed | 2 months and 6 days old | 25 lbs

My puppy is taking 3cc of Benadryl three times a day and a capsule for her skin and coat (prescribed) once a day. Is it safe to put both of them in her food at the same time or should I give them to her separately throughout the day? Forgot to ask the vet today. Also she is crazy hyper and I really need her to calm down, can I up her dose on Benadryl?

1 Answer

Most Helpful Answer

Lauren Jones VMD

Answered By Lauren Jones VMD

Veterinarian

Published on March 6th, 2019

I’m assuming that the capsule prescribed to help with Mia’s skin and coat is a fatty acid fish oil (Omega 3 and/or 6) supplement. Yes, it is perfectly safe to put this with the Benadryl in her food at the same time. Try putting these medications in a small amount of food to assure that she eats them before feeding her the remainder of her meal. Only give the amount of Benadryl that your veterinarian directed - do not increase the dose. The Benadryl may make her a little bit groggy, but if it doesn’t, that’s ok. It’s normal for puppies to be a little hyper! Just offer her plenty of exercise and play time to try to burn off the extra energy. I hope this helps and that all goes well for Mia!
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