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Updated on September 23rd, 2025
Pet's info: Dog | American Pit Bull Terrier | Female | spayed | 5 years and 6 months old | 51 lbs
Can I give my dog Benadryl and Melatonin for anxiety at the same time. It’s raining really bad and hard. Hurricane Delta is heading out way.
2 Answers

Answered By Dr. Melanie, BVSc MS
Veterinarian
Published on October 8th, 2020
Answered By Karly Macon, DVM, MS, CVA Certified Veterinary Acupuncturist
Veterinarian
Published on April 4th, 2017
Benadryl is a very safe medication but I can't legally give you a specific dose because I haven't seen your pet in person. However, if your dog has severe anxiety in the face of storms, benadryl is not an appropriate medication to use because it is not designed for anxiety/fear/stress--it is an antihistamine for allergic reactions. In the future, you need to visit your veterinarian and ask for anxiety medication like Lorazepam (off label) that works very effectively for this purpose. Benadryl will likely never work well for your dog for this purpose.
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