Great Dane leg swelling growing, not walking or eating. What to do?
Poor Axel! Because this swelling keeps getting bigger, I would be concerned that it is a cyst, a benign tumor, or a malignant tumor. I'm not sure what medications he was given, but clearly they aren't working if the swelling has gotten bigger. It's also concerning that he has stopped using the leg, not walking properly, and not eating. I would have Axel seen by the vet again today. I recommend having a fine needle aspirate done on it. To do this, the vet sticks a small needle into the lump to get a sample of it's cells, and examines the cells on a slide under a microscope. It's usually painless to the animal, and relatively quick to perform. Once the cause of the swelling is found, the vet can discuss treatment options.
Updated on September 23rd, 2025