My puppy ate a grape yesterday and is lethargic. Is it kidney failure?

Some dogs can eat grapes without getting ill or having kidney failure, others cannot. Next time you visit a veterinarian with Riker have some blood work done to make sure he has healthy kidneys. Should Riker get lethargic, start drinking a lot of water or has diarrhea or vomits. All these could be signs of kidney disease.

Oh no, poor Rosie! Grapes are highly toxic to dogs and can cause acute kidney failure, leading to signs of lethargy, vomiting and inappetence. Rosie needs to go to an ER vet immediately, as this could be a life-threatening emergency. The vet will be able to examine her, determine her kidney values on lab testing (CBC, chemistry, urinalysis), and start her on IV fluid therapy with other supportive medications. Good luck!

Grape toxicity can cause kidney disease and failure. An increase in drinking and urination along with anorexia and vomiting are common side effects of that. These generally stay within 24 hours with the most severe starting 24-48 hours. So 2 days is the time to monitor for any toxicity

Poor Pots. Yes, I would take him back into the vet now for blood work for baseline kidney values if this hasn't been done yet. If he did get blood work at the vet, then I would wait and bring him back into the vet in three days for additional blood work. If you do see any signs of kidney failure, take him into a vet immediately. Best of luck.

How naughty of Hector to get into some grapes! It is extremely encouraging that his kidney values (particularly the creatinine and BUN) are within a normal range. The SDMA value is thought to be of use in detecting early signs of chronic kidney disease, but is not of much value when concerns about acute kidney disease arise (as in the case of grape ingestion). Remember that there is a wide range of normal to account for individual variation and values at the higher end of this normal range do not typically indicate a problem. I can see that Hector's ALT (a liver value) is mildly elevated, but in all honesty, I do not worry about elevations in this value until they are about twice the upper limits of normal (>240, whereas Hector's value is 181). That said, it is still worth asking your vet if it is possible simply to recheck this value in another week or two. It will most likely return to normal, but if it remains high or increases further, ongoing monitoring of the ALT and further diagnostic testing (bile acid testing, abdominal ultrasound, etc.) may be indicated. I hope this helps to clear up any confusion and that Hector continues to do well after eating grapes!

I would suggest to provide his normal food and monitor closely. If he continue to try to defecate without result he might be constipated. I would also recommend to have a blood test done to check the kidney function. Unfortunately grapes are toxic for dog and can cause damage to the kidneys. Therefore I recommend to see your veterinarian asap to address both issues. Please post again on the forum if you would like to discuss it further. I hope my answer was helpful.