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Why did my dog have an allergic reaction after meds and food?

Updated on September 23rd, 2025

Pet's info: Dog | American Pit Bull Terrier | Male | neutered | 10 years and 5 months old | 68 lbs

Last night, my pet was taken to a veterinarian who he has not seen before, for what was believed to be bronchiole irritation or kennel cough. He was given three injections: Baytril, Kenalog, and an ACE/Torbugesic combination. He was sedated all night, then this morning after feeding him a small amount of food, he developed a SEVERE allergic reaction (hives, diarrhea, vomiting). He's eaten the same food his entire life and has never had a reaction. Are any of these meds contraindicated with food?

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on September 1st, 2017

Hello, thank you for using Petco Pet Education Center, formerly Petcoach. I am sorry your question was not addressed earlier. This is a perplexing situation. Usually, when we see a drug reaction, it occurs within 30 minutes of administration, especially with injectables. This was most likely a delayed type hypersensitivity reaction & not associated with the food consumed. I hope you have conveyed this information to the veterinarian who gave the medications. I would also inform Brew's regular veterinarian of the reaction & make sure a note is placed in the record that one of the medications, or the combination, can cause a significant allergic reaction in Brew. But I do not think the food contributed to the problem. If he is not feeling/doing better very soon, please have him examined. There are other medications that will mitigate the allergic reaction. Hopefully, Brew will be doing great very soon. Take care.
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