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My dog's lab results are abnormal but not medically relevant. Is cancer a concern?

Updated on September 23rd, 2025

Pet's info: Dog | Labrador Retriever | Female | spayed | 8 years old | 65 lbs

My 8 year old Labrador had a vet appointment today. Her doctor did a CBC and said everything looked good. However when I got home I saw the lab work report and a couple things (lymphocytes, monocytes, RDW) were listed abnormal. It also said they were not medically relevant. What does that mean and should I be concerned about her out of range lab results? I worry about a possible cancer. Thanks in advance!

1 Answer

Most Helpful Answer

Sara Farmer, DVM

Answered By Sara Farmer, DVM

Veterinarian

Published on December 16th, 2018

I can see the results, but I'm unable to see the reference ranges for each value which can vary based on the machine so it's a little difficult to say for certain what these changes could mean. It looks to me like the monocytes and lymphocytes (specific types of white blood cells) are a little low - this could be a stress response which is very normal for a dog having it's blood drawn in the hospital. Some dogs simply lie on the lower end of the reference range as well. I can't think of any disease where low lymphocytes and monocytes in the absence of other changes would be significant, and this would not raise a flag for possible cancer in my mind. Red cell distribution width (RDW) gives an idea of the average size of a red blood cell and mean cell hemoglobin concentration (MCH) tells how much hemoglobin is present in each cell - these parameters are really only significant when there is also anemia or low hematocrit. If you have other concerns you should definitely follow up with your vet - it's always easiest for the doctor who has examined the animal and is familiar with the case to interpret lab results!
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