Two Easy Ways to Start Earning Rewards!
Earn 2X Pals Rewards points at Petco
when you use Petco Pay!
Updated on September 23rd, 2025
Pet's info: Cat | Domestic Longhair | Male | unneutered | 9 years and 9 months old | 10 lbs
Can I spray Benadryl on my cats itching skin? He gets real bad sores and licks his hair off
2 Answers

Answered By Daniel Fonza, DVM
Veterinarian
Published on October 4th, 2017
Answered By Jessica Keay, DVM
Veterinarian
Published on June 22nd, 2017
It is always recommended to discuss any new medications with your veterinarian prior to starting, as they known your pet's history and current medications best. We sometimes use benadryl in cats, but sometimes other anthistamines we prescribe such as hydroxyzine, can be more effective. Other times if the itching is intense we may need stronger medication such as a short course of steroids or a medication called apoquel (this is off label use as it is only labeled in dogs). Sometimes we also add fatty acid supplements as well because these can decrease inflammation in the skin and help with itching. I would recommend talking to your vet and letting them know her itching is bad and she needs some medication to make her more comfortable, and they can help decide the safest/best medication for your kitty.
1Pet Parents found this answer helpful