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Updated on September 23rd, 2025
Is it safe to use benadryl cream on a cats hot spot?
2 Answers

Answered By Stacey Anstaett, DVM
Veterinarian
Published on December 6th, 2018
Answered By Dr. Melanie, BVSc MS
Veterinarian
Published on February 3rd, 2017
No, I would not put benadryl cream on it. Although quite safe on superficial wounds, cats groom and ingest most of the topical ointment you apply and therefore should be used only under direct veterinary supervision and if there are no other appropriate options. Many human ointments contain multiple other ingredients which are not necessarily safe to be swallowed. Given that it's only a small dry spot, I wouldn't be worried about it. Keep an eye on it, and if it doesn't heal, you can take Duke into the vet to have it examined.
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