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Is Sileo, a dog sedative, safe for my cat's travel anxiety?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 3 years and 6 months old | 13 lbs

The pet pharmacy gave us sileo as a sedative to use for our cat during traveling. But all I can find online is that it’s for dogs, no mention of cats anywhere. Is sileo safe for cats? Is it effective

1 Answer

Most Helpful Answer

Linda G,  MS, DVM

Answered By Linda G, MS, DVM

Veterinarian

Published on August 30th, 2019

Hello. Yes, the medication in Sileo is used in cats all the time, but actually using this particular product in cats is considered extra-label & therefore you are using this at your own risk. Since the smallest amount that can be dispensed from the tube is one dot, I assume that is the maximum that anyone would want to use on a cat, but PLEASE contact your pharmacy or your veterinarian for the exact amount to be used. Otherwise, I can not recommend the use of Sileo in cats. Thanks for using Petco Pet Education Center, formerly Petcoach.
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