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Kitten URI not improving on antibiotics. When should I call the vet?

Updated on September 23rd, 2025

Pet's info: Cat | Domestic Shorthair | Female | spayed | 7 lbs

I am fostering a 3 week old kitten with a URI. Today is day 4 of her antibiotics doxycycline and I'm not seeing much improvement. After how many days should I consider switching antibiotics? Also is it more important for her to sleep during this time or should I encourage some activity? How often should I use the humidifier? How important is handling her to her health improving?

3 Answers

Most Helpful Answer

Maria DVM

Answered By Maria DVM

Veterinarian

Published on April 19th, 2018

This may be a virus and not a bacterial infection. If that's the case antibiotics will not help and the virus needs to run its course which can take up to two weeks. As long as she isn't getting worse, running a fever and is eating I would keep monitoring her. If at any time she does get worse or isn't getting any better after 7-10 days, I would call your veterinarian. Let her rest unless she wants to play.

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Related Answers from Veterinarians

  • Answered By David Elbeze, DVM, MRCVS

    Veterinarian

    Published on September 22nd, 2017

    You are doing everything in your power at the moment, i can't think of anything else you can do. due to him getting worse it might be a good idea to add some bronchodilatator meds to his antibiotics, you will need to get that from your vet. oxygen therapy is also an option if he seems really lethargic. usually improvement is seen within 3-4 days from the start of the antibiotic course.

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    2Pet Parents found this answer helpful

  • Answered By Dr. Strydom, DVM

    Veterinarian

    Published on July 26th, 2019

    That sounds a bit concerning... If she is eating and drinking and acting pretty normal I guess I would give a few days for the antibiotics to kick in.

    If she is not eating or acting normally (like this breathing pattern is new) then you should get her back tot he vet for a follow-up. X-rays may be needed to check for pneumonia or a diaphragmatic hernia.

    You know her best so if you are worried go with your gut instinct.

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    1Pet Parents found this answer helpful

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