Is my 6-month kitten's high BUN/Creatinine a sign of kidney disease?

His SDMA is normal which is a more reliable marker for kidney function. He may have been mildly dehydrated which can cause creatinine to elevate. Your vet could run a urinalysis to check his urine specific gravity and then recheck his BUN and Creatinine in 3 months to monitor for any increases.

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. Creatinine level of 3.3mg/dL does suggest CRF. If Patch was on iv fluids treatment recently (between these two blood tests), it is possible for CREA level to go down to normal. However, if Patch did not receive any iv fluids, I would suspect one of the reading was incorrect and should be repeated. High BUN suggest kidney disease as well, but it could also be due to dehydration, gastrointestinal bleed, recent feeding and more. Elevated TBIL is also a concern as it could be a sign of liver / gall bladder / bile duct disease. Less commonly, it is due to hemolytic anemia (in that case Patch would have evidence of anemia). Please, get in touch with your local vets as ideally, the blood test should be repeated and should include hematology.

Poor guy. I see elevate liver enzymes (ALT,AST) and kidney values on the paperwork you have attached here. Low hgb means that the red blood cells are not oxygenating well, but if the RBC count is also low (anemic) then that is a sign of chronic kidney failure. Cats can recover from kidney disease depending on the underlying cause. An abdominal ultrasound is needed to determine the cause of the kidney failure exactly, or a positive response to bloodwork is used as a means of determining a positive outcome. In most situations we treat the pet with fluid therapy to help idurese (flush out) the harmful toxins (BUN, CREA), get the pet started on a prescription kidney diet (ie. Hill's K/D, Royal Canin Renal) and also a supplement (Azodyl- which helps to remove toxins from the gut) can be given as well. The most concerning values for me on this bloodwork are the liver values (AST, ALT). It is not common for a cat to be in both kidney failure and to have abnormal liver values concurrently. THis raises suspicions for infectious diseases such as any number of tick diseases. I would recommend discussing with your vet about possibly doing a tick panel, if the history indicates tick exposure is probable. Also a FeLV/FIV test may also be indicated, depending on the complete CBC results, which you didn't post here. At the very least a liver protectant medication should be started, which is typically a medicine called Denamarin. Additional treatment may be needed depending on the underlying cause for the liver abnormalities. If you would like to discuss Toby's case further, then please feel free to request a consultatoin with either myself or another expert here. Toby's case is definitely a more complicated case where it is best to have a complete dialogue back and forth to get all the information you need to make the best decision moving forward with his care. I wish you all the best moving forward with Toby's care and I hope that he makes a full and speedy recovery. Take care.

I don’t think this shows renal disease. His creatine is normal with a slightly elevated BUN. To me this is more an indication of mild dehydration than kidney disease. He is slightly anemic also which is not uncommon in senior animals but may indicate a chronic medical problem. The eosinophils are slightly elevated which can be due to allergies or intestinal parasites. Basically for a thirteen year old cat there is nothing here that is overly concerning. Bloodwork is just a moment in time though so if you’re concerned I would repeat it again in a month or two so you can see if there is a trend indicating progression of a medical problem or kidney disease. Thanks for using Petco Pet Education Center, formerly Petcoach to help you care for Beau.

The elevated creatinine on it's own does not indicate kidney disease. Remember, this blood was taken at one second in time, he may have recently eaten or been a bit dehydrated at the time which caused the CREA to be a bit elevated. You can not determine kidney disease with just this one test. If you are concerned this should be repeated when he is fasted and a urine test should be done at the same time. If you want to give him a kidney supplement that will help to support kidney function you can use this: https://worldtails.securevetsource.com/itemView/view/198944_HomeDelivery.pml?productId=132504

Kudos to you for being such a diligent owner to your senior kitty! SDMA is technically a more sensitive measure of early kidney disease so the fact that it is still normal is excellent news. You’re right that the BUN and creatinine are borderline high, however mild dehydration can do this too. Therefore, if I see values like that in conjunction with highly concentrated urine and a normal SDMA, I’m not going to do anything except to continue monitoring. If the urine is dilute, there is protein in the urine, etc. then I investigate further. All in all, I agree that there is not much cause for concern but I’d recheck in 3-6 months. Best wishes to you and Tony!

Hi there and thank you for using Petco Pet Education Center, formerly Petcoach to address your concern. BUN and Creatinine typically have an intimate relationship on blood work, meaning that when one is elevated, the other is typically elevated as well. There are relatively few conditions that would have an elevated Creatinine without the BUN being elevated. These are typically due to muscle breakdown which would release more creatinine in the blood. Exercise could produce such an increase. Pathologic muscle breakdown would produce sharp levels but such conditions would likely be accompanied by symptoms such as weakness and lethargy in particular. The value of 6.1 is high, which could indicate any of the above or this could potentially be a lab error. I would consider having the blood retested to check and make sure this value is correct. It may be wise to have it sent to a laboratory as well to ensure the values are correct. I hope this helps! Please let me know if you have any other questions or concerns.