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Updated on September 23rd, 2025
Pet's info: Cat | Domestic Longhair | Male | neutered | 6 years and 1 month old | 7.7 lbs
We have a very sick cat who is FIV positive. He had no symptoms until about 7 months ago when he developed upper respiratory disease. He tested positive for mycoplasma felis and Chryseobacterium indologenes. Orbifloxacin had limited effect. Today he has eaten a little but has lost 34% body weight. He has been off drugs for 3 weeks but was treated today for anemia. Blood work shows low hemoglobin and MCH but normal lymphocytes. Should he be treated for these two bacteria above? Can we save him?
2 Answers

Answered By Lauren Jones VMD
Veterinarian
Published on February 21st, 2018
Answered By Lindsey Edwards MVB, BSc, IVCA
Veterinarian
Published on February 24th, 2018
Poor Atticus - he sounds very unwell and such a dramatic weight loss is very concerning, especially in an FIV positive cat. I have not used LTCI (it is not yet available where I work) but the early results and mode of action do look very promising in reducing the impact of FIV on patients and supporting the debilitated immune system. I would recommend retesting for Mycoplasma/Chryseobacrium to see if they have cleared following the initial treatment and improvement in his natural immunity; alternative antibiotics may be required if still positive. Given his low blood count I would be particularly concerned about a persistent Mycoplasma infection (this infection lives within and destroys red blood cells)
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