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Why is my cat losing weight with chronic diarrhea and normal tests?

Updated on September 23rd, 2025

Pet's info: Cat | Mixed Breed | Male | neutered | 9 lbs

Diarea over 2 years. All blood tests come back ok. Thyroid ok. Cat acts normal.Loses weight, but was stable for over 6 months.Started again Vet has been giving Depomedral shot, after a few days seemed to work.Not this time. At wits end

1 Answer

Most Helpful Answer

Answered By Lauren Jones VMD

Veterinarian

Published on June 13th, 2017

It sounds as though you and Schumacher have been through a lot over the past 2 years! Given his weight loss, chronic diarrhea, normal blood work and initial response to depomedrol, chronic pancreatitis or primary intestinal issues, such as inflammatory bowel disease or lymphoma would be my main concerns. In this situation, further diagnostic testing is often needed to try to get to the bottom of this issue. Some tests include vitamin absorption and pancreatic blood tests (B12, folate, TLI, fPL) and an abdominal ultrasound to look at his internal organs, intestinal thickness, lymph nodes, etc. In some cases, biopsies are needed to differentiate between different conditions so that the most appropriate treatment can be started. Cats with inflammatory bowel disease or lymphoma often benefit from long-term steroids, antibiotics and prescription diets to control their clinical signs. I hope that all goes well for Schumacher!

1Pet Parents found this answer helpful

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