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My cat's Frontline isn't working. Can I switch to Revolution now?

Updated on September 23rd, 2025

Pet's info: Cat | Russian Blue | Male | unneutered | 5 lbs

I have my cat frontline plus on aug 1st but it's not working can I switch to revolution now or do I have to wait to 30 days to apply it

3 Answers

Most Helpful Answer

David Darvishian

Answered By David Darvishian

Veterinarian

Published on August 17th, 2017

Hi and thanks for using Petco Pet Education Center, formerly Petcoach! Sorry to hear that Negrito is having a flea problem. Since Frontline Plus and Revolution are 2 totally different products, you can apply the Revolution now and not wait until the full month is done. You shouldn't see any problems and if you do, I would advise calling your vet. Very occasionally cats and dogs will have problems with one topical product and not another. Just make sure that you apply it correctly right up over the neck where Negrito can't lick it off as soon as it is applied. Good luck and I hope Revolution works well for him. I do believe we are starting to see some problems with Frontline as I have witnessed the same problem last summer when using Frontline.
Vote Icon28Pet Parents found this answer helpful

Related Answers from Veterinarians

  • Answered By Dr. Macartney, BVet Med, MRCVS

    Veterinarian

    I am so sorry to hear this, I also do not see much success with frontline. I wooold not advise using an additional medication until the 30 days is over. This will ensure that Negrito's system is not overwhelmed. You could try treating your home in the meantime as fleas spend most of their lifecycle off iof cats and dogs and in the environment.

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    6Pet Parents found this answer helpful

  • Answered By Dr. Massimo Orioles, DVM, Cert AVP, MRCVS

    Veterinarian

    Published on October 7th, 2019

    It would be best to wait another week before applying Revolution. Unfortunately it seems like Frontline is not a good option anymore as I have been having negative feedback from many clients about its efficacy.

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    1Pet Parents found this answer helpful

Smart Picks for Smart Questions

Vet Q & A
Cat's flea treatment not working. Can I safely apply Frontline now?
Since both Sentry and Frontline use the same active ingredient (fipronil) it is unlikely that you will see better protection switching to the Frontline. You will need to choose a product with a different ingredient, like Advantage or Revolution or a Seresto collar. If you choose to use another topical, I would recommend bathing your kitty today to remove any remnants of the Sentry, and wait 3 days to apply the next topical. It is important to wait after bathing so that the natural body oils have time to coat the skin to ensure adequate absorption. You do not need to wait or bathe to use a Seresto collar.
Updated on September 23rd, 2025
Health & Wellness
Is it safe to apply Revolution after Frontline Plus for cat fleas?
Hi there I'm sorry to hear about Finn's troubles. From what I know Revolution and frontline can ve safely combined. Just be sure that if you bath Finn you wait the appropriate amount of time afterwards before applying the Revolution. I usually recommend 2 days.
Updated on September 23rd, 2025
Health & Wellness
My cat got Frontline Plus and Revolution. Is this combination safe?
Since Frontline plus is a different type of flea preventive (fipronil + a larval development inhibitor) from Revolution (an avermectin) there should be no problem. There is no adverse interaction reported that I could find.
Updated on September 23rd, 2025
Medications
My cat gets Revolution. Can I add Frontline Plus for tick prevention?
Harriett is a cutie! Yes you can use frontline as well but I would recommend to separate the two medicines by two weeks. For instance you apply revolution on the 1st then frontline on the 15th then revolution on the 1st again and so on. I hope this helps!
Updated on September 23rd, 2025
Medications
Is it safe to use Revolution and Frontline together for kitten mites?
I'm sorry to hear about your issue with Cheyletiella. They are a bothersome parasite to deal with! Apply Revolution every 2 weeks for 3 treatments (use appropriate dose for your kittens' weight). You can use Frontline Plus as well if you feel you aren't getting the results you wanted at the dosage of Revolution stated above. Fontline Plus can be applied every 2 weeks at the correct dose based off body weight for this problem. You should also use a lime silver dip or topical flea product to clean the kittens. Diluted bleach 1 part bleach:9 parts water sprayed on all surfaces and allows to sit for 10 minutes before wiping clean should help. All bedding and toys should be washed in hot water or thrown away. Good luck and thank you for contacting me today!
Updated on September 23rd, 2025
Health & Wellness
Revolution ran off my cat. How to apply it correctly? When to reapply?
Hi, thanks for using Petco Pet Education Center, formerly Petcoach! Revolution can be applied every 4 weeks. There is also Bravecto which is a topical that lasts 3 months. The Seresto collar lasts 8 months and comfortis is a monthly pill. For the last 2 there is no application error which is nice. Otherwise, part the fur to the skin and apply the contents of the Revolution to that spot and then put the hair back. It is normal for some of the liquid to go down over the hair. Maybe try the base of her skull or shoulder blade area so it doesn't go down the sides. I hope this helps!
Updated on September 23rd, 2025
Medications
My kitten has mites. Is it safe to use Frontline after Revolution?
It is generally ok to apply these two different topical medications 15 days apart but I would make sure that your kitten is at least 8 weeks old before using a fipronil based product. Good luck, those mites always make me feel itchy, I feel for you and your kitten!
Updated on September 23rd, 2025

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