Cat swallowed buprenorphine instead of cheek pouch. Is it okay?

This represents a pretty substantial overdose. Corbett got about 2.5 times more than the highest published dose for pain relief. However, it's thought that buprenorphine has a high index of safety, and even large overdoses don't usually cause serious effects. I'm assuming you gave it on the gums ("transmucousally") as that's how it's typically prescribed for pain relief at home in cats. Because of that method of administration, there's no way to remove the drug from his system by inducing vomiting. There is a reversal agent that is somewhat effective, but may have to be given in multiple doses due to the way buprenorphine works. The drug is naloxone, and your veterinarian should have this drug. Because the signs of overdose can be concerning (vocalization, ataxia, hypersalivation, decreased body temperature, and lethargy) my best recommendation would be for you to take Corbett back to your veterinarian for administration of this drug, so that the overdosage can be averted.

With your cat's weight being 11 pounds, there is a dose range for Buprenorphine that fits into the amount you gave. He may be a little sleepier and I would not continue the double dose unless your vet recommends it. Keep an eye on him in case he is too sleepy, but he should be ok. Signs of a problem would be too sleepy, a slower breathing rate.

Buprenorphine has few side effects in cats with the most common one being sedation. It may be Sofia is feeling a bit nauseous from vomiting, which can happen. If you are very concerned about her, you can take her into the vet. Best of luck.

Hello and thank you for contacting Petco Pet Education Center, formerly Petcoach. Gaga will be very sleepy and lethargic after the extra dose of Buprenex but the symptoms should wear off within 6-8hrs. However, in unlikely case that Gaga is overexcited, dysphoric or she is deeply sedated, you should get in touch with your local vets right away.

I am sorry we couldn't get to your question earlier. Hopefully Sitara is back to normal now. The symptoms you have described are consistent with opioid use (which is what Buprenorphine is). I would not be overly concerned. I am more concerned about her dental disease and the plan to treat that, since the pain medications and antibiotics won't fix that particular problem. She needs a full dental cleaning under anesthesia and may need her teeth extracted if stomatitis is a concern. https://www.petcoach.co/article/gingivitis-and-stomatitis-in-cats/

I am not sure how you are able to tell that he hasn't slept for 24 hrs unless you are also up yourself the entire time. Chances are he has slept somewhat, but these are still concerning symptoms that he may be having an adverse reaction to the medicaiton or that a lower dose is needed for him. Also it is concerning if he hasn't gone potty. Male neutered cats can get urinary blockages which causes them to be very vocal, lethargic and strain to urinate. I would advise taking him to your local vet right away for an evaluation and potentially stopping his medication until he is deemed healthy enough to proceed with either this medicaiton or an alternative. I hope that Cucho is able to make a full and speedy recovery. Best wishes and take care.

Thank you for contacting Petco Pet Education Center, formerly Petcoach with your question about Boo. The dose for cats can be up to 1mg/kg. 1mg/kg equals 0.001mg/l, or 1mg/ml. Based on this, he could have up to 4.8ml, so this is within the dose. I hope this helps!